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Cardiology > Loop and thiazide diuretics > Flashcards

Loop and thiazide diuretics Flashcards

1
Q

what is the site of action of loop diuretics

A

thick ascending LOH

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2
Q

how do loop diuretics work

A

block Na/Cl/K cotransporter

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3
Q

what is the site of action of thiazide diuretics

A

early DCT

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4
Q

how do thiazide diuretics work

A

block thiazide sensitive NaCl symporter - inhibit resorption of sodium and chloride

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5
Q

what effect do thiazides have on calcium

A

hypocalcaemia

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6
Q

give some side effects of loop and thiazide diuretics

A 
hyponatraemia
hypokalaemia
hypochloraemia
hyperglycaemia
hyperuricaemia
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7
Q

what effect do loop diuretics have on calcium

A

hypercalcaemia

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Cardiology (19 decks)

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