Long Term Control of Blood Pressure Flashcards
1
Q
What happens if the collecting duct is very permeable?
A
- Lots of water reabsorption
- Small volume of hyper-osmotic urine
- Increases plasma volume
2
Q
What does renin do?
A
- Converts angiotensin into angiotensin I
- ANG I turns into ANG II by angiotensin converting enzyme (ACE)
- ## When ANG II reaches the adrenal gland, aldersterone is synthesised
3
Q
What does renin do?
A
- Converts angiotensin into angiotensin I
- ANG I turns into ANG II by angiotensin converting enzyme (ACE)
- When ANG II reaches the adrenal gland, aldersterone is synthesised
4
Q
What triggers renin production?
A
- Activation of sympathetic nerves to the juxtaglomerular apparatus
- Decreased distension of afferent arterioles (the renal baroreflex)
- Decreased delivery of Na+/Cl- through the tubule
(All of the above signal reduced MAP)
5
Q
Explain why RAAS is a negative feedback system
A
- Multiple mechanisms detects drop in MAP
- Stimulates renin production
- This evokes multiple mechanisms that increases MAP
6
Q
Where is ADH produced?
A
- Synthesised in the hypothalamus
- Released from the posterior pituitary gland
7
Q
Where is ADH produced?
A
- Synthesised in the hypothalamus
- Released from the posterior pituitary gland
8
Q
What triggers ADH release?
A
- Decrease in blood volume (sensed by cardiopulmonary baroreceptors and relayed via the medullary cardiovascular centres)
- Increase in osmolarity of interstitial fluid (sensed by osmoreceptors in hypothalamus)
- Circulating angiotensin II (triggered by RAAS)
(All of the above signal reduced MAP)
9
Q
What does ADH do?
A
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