London Review On Dementia Flashcards
0
Q
3 parts of prefrontal cortex and corresponding deficit
A
Dorsolateral- cognitive, executive
Orbitofrontal-disinhibition, personality
Medial frontal-apathy
1
Q
CJD
A
- Classic triad of cortex: spongiform vacuolation, loss of neurons, astrocyte cell proliferation
- EEG abnormalities present in almost all patients, though are not specific: slow and irregular background rhythm, periodic complex discharges
- CT and MRI: diffuse cortical atrophy
- PET: heterogeneously decreased uptake throughout the cortex.