Locomotor Drugs Examples

Question 1

Simple analgesics

Answer 1

Paracetemol (often combined with codeine - co-codamol, or dihydrocodein - co-dydramol

Question 2

Opioid analgesics

Answer 2

High efficacy: Morphine, methadone. Low efficacy: codeine, dihydrocodeine, tramadol

Question 3

NSAIDs

Answer 3

non-selective: Ibuprofen, aspirin, naproxen. Selective COX-2: celecoxib (reduced peptic ulcer instance, but higher rate of cardiovascular events, so limited use now)

Question 4

Drugs for neuropathic pain (anti-epileptics)

Answer 4

carbamazepine, also antiepileptics gabapentin, phenytoin. Antidepressants: amitriptyline

Question 5

Anti-migraine

Answer 5

sumatriptan, almotriptan … triptans

Question 6

Nitrates

Answer 6

Glyceryl trinitrate, isosorbide mononitrate

Question 7

Local anaesthetics

Answer 7

lidocaine, cocaine, prilocaine, bupivacaine

local anaesthetics plus adrenaline

Question 8

Corticosteroids

Answer 8

prednisolone, hydrocortisone

Question 9

DMARDs

Answer 9

methotrexate

sulfasalazine

Question 10

Cytokine inhibitor

Answer 10

infliximab

Question 11

Glycosaminoglycan anticoagulant

Answer 11

heparin

Question 12

Bisphosphates

Answer 12

Alendronic acid

Question 13

Hormones

Answer 13

Oestrogen/ HRT
Calcitonin
PTH

Question 14

Oestrogen receptor modulators

Answer 14

raloxifene

Question 15

Vitamin D

Answer 15

dairy products, saltwater fish, liver, egg yolks, oral ergocalciferol or alfacalcidol