Localization Flashcards

1
Q

What is the differences between UMNL & LMNL?

A

UMNL LMNL

  • above anterior horn cells - AHC, motor fibers, or neuromuscular junction
  • increased spasticity - reduced
  • clonus
  • increased reflexes - reduced or absent reflexes
    • Babinski sign - normal or absent Babinski
  • absent fasciculations - present
  • wasting late - wasting present
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2
Q

What are the characteristics of cortical lesions?

A
  • always opposite side
  • based on the lobe involved (personality changes, weakness, aphasia, or visual field deficits)
  • usually due to embolic wedge shaped infarcts, thrombotic occlusion of a large artery, or intercerebrayl hematoma
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3
Q

What are the signs & symptoms of a frontal lobe lesion?

A

Frontal both

  • intellectual impairment
  • personality changes
  • urinary incontinence
  • mono paresis or hemiparesis

Frontal Left
- Broca’s Aphasia

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4
Q

What are the signs & symptoms of a temporal lobe lesion?

A

Temporo-parietal left

  • Wernnicke’s aphasia
  • acalculia
  • alexia
  • agraphia
  • homonymous field defect
  • right-left disorientation

Temporal right

  • confusional states
  • failure to recognize faces
  • homonymous field defects
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5
Q

What are the signs & symptoms of a parietal lobe lesion?

A

Parietal both

  • contralateral sensory loss
  • agraphaesthesia
  • homonymous field defect

Parietal right

  • dressing apraxia
  • failure to recognize faces

Parietal left
- limb apraxia

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6
Q

What are the signs & symptoms of a occipital lobe lesion?

A
  • visual field defects
  • visuospatial defects
  • disturbances of visual recognition
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7
Q

What is the blood supply to the brain?

A

Anterior Cerebral artery
- anteromedial surface

Middle Cerebral artery
- lateral surface

Posterior cerebral artery
- posterior & inferior surface

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8
Q

What are there types of aphasia?

A

Broca’s aphasia

  • non-fluent
  • broken speech

Wernicke’s aphasia

  • fluent
  • word salad
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9
Q

What are the lesions that could affect the optic nerve pathway?

A

1- Lesion at optic nerve -> total blindness of ipsilateral eye
2- lesion at optic chiasm -> bitemporal heteronymous hemianopia
3- at optic radiation -> contralateral homonymous hemianopia
4- close to calcarine sulcus -> contralateral homonymous hemianopia with macular sparing

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10
Q

injury to the corticospinal tract leads to what type of lesion?

A

UMNL

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11
Q

What is the hallmark of brainstem injury?

A
  • accompanying cranial nerve deficits with the motor & sensory deficits
  • the corresponding cranial nerves will show LMNL
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12
Q

What is the hallmark of cerebellar lesions?

A

ipsilateral ataxia, dysarthria, & nystagmus

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13
Q

What is the hallmark of spinal cord lesions?

A

symmetric UMNL pattern weakness with spinal sensory level

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14
Q

What is the most common cause of cord transection?

A
  • TRAUMA
  • tumors
  • disc herniation
  • demyelinating diseases
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15
Q

What is the hallmark of AHC lesions?

A
  • LMNL
  • purely MOTOR -> only weakness
  • no tingling or numbness

like ALS, SMA, & Polio

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16
Q

What is the hallmark of peripheral nerve lesions?

A

mixed sensory & motor symptoms of LMNL pattern

like diabetes, GBS, or HIV

17
Q

What is the hallmark of neuromuscular junction lesions?

A

diffuse weakness with FATIGUABILITY
- includes ocular & bulbar muscles

like myasthenia gravis

18
Q

What is the hallmark for myopathies?

A

the muscle fibers only

  • weakness of PROXIMAL & axial muscles
  • NO sensory deficits
  • elevated CK

like dermatomyositis, infectious myositis, drugs