Local pharm of LA's

Question 1

A fibers: size and myelinated?

Answer 1

large myelinated

Question 2

C fibers: size and myelinated?

Answer 2

small and unmyelinated

Question 3

for the activation gate to be ready, it must be …

Answer 3

closed

Question 4

3 parts of an anesthetic and which os hydrophilic and hydrophobic?

Answer 4

aromatic- hydrophobic

ester or amide

amino- hydrophilic

Question 5

aqueous distribution constant, Q reflects the ability to …. and it correlates with …

Answer 5

penetrate hydrophobic tissue

duration

Question 6

dissociation constant, pKa reflects the proportion of … to … molecules and it correlates with

Answer 6

ionized to unionized

onset

Question 7

susceptibility to blockade from most to least:

Answer 7

dull pain
warmth
cold
sharp pain
touch 
pressure
proprioception

DWCSTPP