Local Anesthetics and Regional Anesthesia Flashcards
Local anesthetics prevent depolarization of nerve by blocking _____
influx of NA, blocks fast NA channels
Which fibers are blocked easier by local anesthetics?
small fibers
Order of a Block:
B fibers
C
A-
delta, gamma, beta, alpha
Two types of locals:
esters and amides
Amides are cleared by reaction in ______
liver
Esters are broken down by ______
plasma cholinesterase
Types of esters for infiltration
procaine (novacaine)
cholorprocaine (Nesacaine)
tetracaine (pontocaine)
Max plain dose of procaine (novacaine)
350-600 mg
max with epinephrine dose of chloroprocaine (nescaine)
1000 mg
Max with epinephrine dose of procaine (novacaine)
1000 mg
Max plain dose of chloroprocaine (nesacaine)
800 mg
other name for procaine
novacaine
other name for lidocaine
xylocaine
other name for tetracaine
pontocaine
other name for chloroprocaine
nesacaine
max plain dose of tetracaine
100 mg
types of amides
lidocaine (xylocaine)
mepivacaine (carbocaine)
bupivicaine (marcaine)
other name for mepivacaine
carbocaine
other name for bupivicaine
marcaine
Lidocaine 0.5-1% max plain dose
4.5 mg/kg or 300 mg
max with epinephrine dose of lidocaine
7 mg/kg or 500 mg
Mepivacaine 0.5-1% max plain dose
300 mg or 7mg/kg
max with epinephrine dose for Mepivacaine
500 mg
Bupivicaine 0.25% max plain dose
2.5mg/kg or 150 mg
max with epinephrine dose of Bupivicaine
225mg or 3mg/kg
four types of regional anesthesia
local infiltration
bier block IV
peripheral nerve blocks
central block
3 types of central nerve blocks
epidural
caudal
spinal
Who can inject local infiltration?
surgeon
podiatrist
dentist
indications for a bier block
brief procedure of hand or forearm
ex: carpal tunnel repair
explain technique for bier block
20g IV in operative arm with extension tubing with 10 ml syringe, double pneumatic tourniquet on operative upper arm. elevate arm, then esmarch wrap distal to proximal. inflate distal cuff, then proximal. inflate to 250-300mHG, esmarch off, distal cuff deflated
what dose of lidocaine 0.5% is administered during a bier block
3mg/kg - 40-50 ml injected slowly into IV
complications of a bier block
accidental tourniquet release/leak
injection of local into the epidural space
epidural
two techniques of a epidural
hanging drop and loss of resistance technique
what is the test dose of 1.5% lidocaine with epinephrine
1:200,000 mcg 3-5 ml Total
names of epidural anesthetics
chloroprocaine (nescaine)
lidocaine
bupivicaine (marcaine)
ropivacaine
plain dose of chloroprocaine 2-3%
200-750 mg
dose of lidocaine 1-2% for epidural
150-300 mg
dose of bupivicaine 0.25-0.5% for epidural
50-100 mg
dose of ropivacaine 0.25-1% for epidural
75-250 mg
caudals are typical in what patient population?
kids
injection of local into the subarachnoid space at lower lumbar area?
spinal
names of drugs given during spinal:
tetracaine (pontacaine)
chloroprocaine
lidocaine
bupivicaine
ropivacaine
plain dose of tetracaine for a spinal
8-15 mg
dose with epinephrine with tetracaine for a spinal
0.1-0.2 mg
dose of chlorprocaine for a spinal
40-60 mg
epinephrine is not recommended for which drugs
chlorprocaine, lidocaine, bupivicaine, ropivacaine
dose of lidocaine 5% for a spinal
75-100 mg
dose of bupivicaine 0.5-0.75% for a spinal
12-20 mg
dose of ropivacaine 0.5-1% for a spinal
18-25 mg
local mixed with sterile H20
hypobaric
local mixed with spinal fluid/NSS
isobaric
local mixed with D10
hyperbaric
indications for a spinal/epidural
lower extremity/hip procedure
lower abdomen, groin, perineum, urologic, rectal, ob procedure
absolute contraindications for a spinal or epidural
refusal
infection at site
sepsis
severe hypovolemia
coagulation abnormaity
increase ICP
relative contraindications for a spinal/epidural
infection peripheral to site
neurologic disorders
heparin/aspirin
back pain or prior lumbar surgery
hypovolemia
uncoperative patient or surgeon
cardiovascular effects of a Spinal
decrease HR
decrease venous return
decrease BP
respiratory effect of spinal
intercostal paralysis
side effects of spinal block
sympathetic nervous system block
hypothermia
maintains peristalsis- contacted GI tract
order of spinal blockade
sympathetic
temperature
pain
touch
pressure
motor
vibratory
proprioception
how to treat hypotension from a spinal
prehydrate with fluids- 500-1000ml
ephedrine 5-10 mg/iv
complications of a spinal
hypotension
post dural puncture headache
tinnitus
diplopia
how to treat a post dural puncture headache from a spinal
analgesics
bedrest
hydration
caffeine infusion
blood patch
ways to decrease incidence of the post dural Headache
smaller needle
turning bevel to side
paramedian
round/blunt tip
hydration
complications of a epidural
hypotension
accidental spinal
signs and symptoms of local drug toxicity
tinnitus
light headed
dizzy
slurred speech
confusion
circumoral numbness
metallic taste
low HR and BP
arrhythmias
seizures
death