Local Anesthetics and Regional Anesthesia Flashcards
Local anesthetics prevent depolarization of nerve by blocking _____
influx of NA, blocks fast NA channels
Which fibers are blocked easier by local anesthetics?
small fibers
Order of a Block:
B fibers
C
A-
delta, gamma, beta, alpha
Two types of locals:
esters and amides
Amides are cleared by reaction in ______
liver
Esters are broken down by ______
plasma cholinesterase
Types of esters for infiltration
procaine (novacaine)
cholorprocaine (Nesacaine)
tetracaine (pontocaine)
Max plain dose of procaine (novacaine)
350-600 mg
max with epinephrine dose of chloroprocaine (nescaine)
1000 mg
Max with epinephrine dose of procaine (novacaine)
1000 mg
Max plain dose of chloroprocaine (nesacaine)
800 mg
other name for procaine
novacaine
other name for lidocaine
xylocaine
other name for tetracaine
pontocaine
other name for chloroprocaine
nesacaine
max plain dose of tetracaine
100 mg
types of amides
lidocaine (xylocaine)
mepivacaine (carbocaine)
bupivicaine (marcaine)
other name for mepivacaine
carbocaine
other name for bupivicaine
marcaine
Lidocaine 0.5-1% max plain dose
4.5 mg/kg or 300 mg
max with epinephrine dose of lidocaine
7 mg/kg or 500 mg
Mepivacaine 0.5-1% max plain dose
300 mg or 7mg/kg
max with epinephrine dose for Mepivacaine
500 mg
Bupivicaine 0.25% max plain dose
2.5mg/kg or 150 mg
max with epinephrine dose of Bupivicaine
225mg or 3mg/kg
four types of regional anesthesia
local infiltration
bier block IV
peripheral nerve blocks
central block