Local Anesthetics

Question 1

Local anesthetic which has the shortest half-life.

Answer 1

PROCAINE (1 to 2 minutes)

Question 2

ROPIVACAINE

Answer 2

Longest half-life (4.2 hours).

Question 3

Why should we not injecf LIDOCAINE into abscess?

Answer 3

It won’t work due to acidic environment (below pKA= protinated form predominates, so it can’t penetrate tissues).

Question 4

Toxic dose of LIDOCAINE

Answer 4

Toxic dose: 5 mg/kg for Any Drug or solution, 1% = 10 mg/mL