Antimetabolites Flashcards
1
Q
Treatment of lymphomas and GTN
A
Methotrexate
2
Q
Oral S/E of Methotrexate
A
Stomatitis
3
Q
Treatment of acute leukemias
A
6-mercaptopurine
*Azathioprine
4
Q
Side effects of 6-mercaptopurine
A
Myelosuppression, hepatoxicity, metabolism Inhibited by Allupurinol.
5
Q
Treatment of colorectal and skin cancer
A
5-FU
6
Q
Causes of Thymine-less death of cells
A
5-FU
7
Q
True or False:
Myelosuppression is a side effect of 5-FU?
A
True
8
Q
CYtarabine
A
CML treatment (blast Crisis)
Most specific for S phase of The cell cycle
9
Q
Gemcitabine MOA
A
Inhibits ribonucleotide reductase,
Treatment of Pancreatic cancer
10
Q
Treatment of Pancreatic CA
A
Gemcitabine
