Local anesthetics Flashcards
1
Q
local anesthetics MOA
A
reduce the influx of sodium ions, prevent depolarization of the membrane and blcoking conduction of action potential
2
Q
amides example and where is it metabolised
A
metabolized in the liver
ex: lidocaine
3
Q
esters example and where is it metabolised
A
metabolised in plasma
more toxic and more allergic than amides
cocaine is an example
4
Q
lidocaine uses
A
AV nodal arrythmias , especially prohylaxis
5
Q
which amide is faster and longer acting as well as safest in children
A
lidocaine
6
Q
lidocaine AE
A
CNS excitation
seizures
vasodilation
hypotension
arrythmias