Local Anesthesia for Pediatric Pts Flashcards
________ is crucial to provide good care and have the child behave as well
Profound local anesthesia
all local anesthetics are what?
weak bases
which end of the LA is hydrophilic?
Amine end
which end of the LA is lipophilic?
aromatic
where are amides metabolized?
liver by P450 enzyme
are amides hypoallergenic?
yes but the true allergy are rare
when are esters applied?
in topical situations
where are esters metabolized?
pseudocholinesterase
are esters hypoallergenic?
no (they are hyperallergenic)
what is an example of an ester LA?
benzocaine
what and where does the acidic part of the LA do?
- in carpule
- keeps anesthetic on either the outside of the nerve sheath or the inside of the nerve sheath
what and where does the basic part of the LA do?
- once in the tissue
- allows the anesthetic to cross the lipid bilayer of the nerve sheath
how many mls of LA are in a cartridge?
-1.7ml
how many mg of lido are in 1 cartridge of 2% lido?
34mg
how many mg of articaine are in 1 cartridge of 4% articaine?
68mg