Local Anaesthetics

Question 1

Adrenaline

Answer 1

Vasoconstrictor
Administered with local anaesthetic to localise more

Question 2

Lidocaine

Answer 2

Local anaesthetic
Amide intermediate chain
Rapid onset
Medium duration
2hr plasma half life
Good tissue penetration
Can cause bradycardia, decreased cardiac output

Question 3

Bupivacaine

Answer 3

Local anaesthetic
Amide intermediate chain
Slow onset
Long duration
Moderate tissue penetration
2hr plasma half life
Greater cardio toxicity than lidocaine

Question 4

Benzocaine

Answer 4

Local anaesthetic
Very slow onset
Very long duration
Very rapid tissue penetration

Question 5

Procaine

Answer 5

Local anaesthetic
Ester intermediate chain
Injectable
Used with adrenaline