Local Anaesthetic Flashcards

1
Q

What nerve supplies the maxillary teeth?

A

Anterior, middle and posterior branches of the maxillary division of Trigeminal nerve (CN V)

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2
Q

What nerve supples the soft tissues of the palatal surfaces?

A

Long sphenopalatine nerve and greater palatine nerves

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3
Q

For papillary injections where is the needle injected?

A

Roughly at level of cervical margin

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4
Q

What nerve supplies the lower teeth?

A

Mandibular division of the Trigeminal nerve

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5
Q

What nerve supples the lingual soft tissues of lower teeth?

A

Lingual nerve

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6
Q

What nerve supplies the buccal soft tissues?

A

Long buccal nerve

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7
Q

What is the duration of action of Lidocaine on the pulp?

A

1hr (60 mins)

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8
Q

What is the duration of action of Lidocaine on soft tissue?

A

170mins (just under 3 hours)

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9
Q

What is the duration of action of Articaine on the pulp?

A

60mins

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10
Q

What is the duration of action of Articaine on the soft tissue?

A

190mins (just over 3 hours)

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11
Q

Which 2 LAs contain adrenaline?

A

Lidocaine and Articaine

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12
Q

Which LA can be used when adrenaline is contraindicated?

A

Prilocaine (with Felypressin) and Mepivacaine (plain solution)

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13
Q

What is the maximum dosage of Lidocaine that can be given to a patient (assuming 70kg)?

A

4.5 cartridges

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14
Q

What is the maximum dosage of Articaine that can be given to a patient (assuming 70kg)?

A

4 cartridges

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15
Q

Should you use Articaine on a pregnant patient?

A

NO

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16
Q

Which patients should you be cautious with when using articaine?

A

Lung disorders (asthma), liver/kidney/thyroid problems, Diabetes mellitus, history of epilepsy

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17
Q

What percentage of Lidocaine and adrenaline is present?

A

Lidocaine Hyderochloride (2% and adrenaline 1:80,000)

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18
Q

What percentage of Articaine and adrenaline is present?

A

Articaine 4% and Adrenaline 1:100,000

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19
Q

What percentage of Prilocaine Hydrochloride and felypressin is present?

A

Prilocaine hydrochloride 3% and felypressin 0.03 IU/ml

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20
Q

When might you use mepivacaine hydrochloride ?

A

When the use of vasoconstrictor is contraindicated (pt with severe hypertension or unstable cardiac rhythm)

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21
Q

What are the landmarks for buccal infiltrations?

A

Mucobuccal fold parallel to the long axis the tooth

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22
Q

What is the dosage for maxillary infiltrations

A

Up to 1/2 cartridge

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23
Q

What does the nasopalatine block anaesthetise?

A

Anterior portion of the hard palate (both hard and soft tissues) from the mesial aspect of the right and left premolars

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24
Q

What are landmarks for nasopalatine block?

A

Central incisors, incisive papilla and incisive foramen

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25
Q

What is in the inject site for a nasopalatine block?

A

Soft tissue just lateral to the incisive papilla, 1cm palatal to the maxillary central incisors

26
Q

What is the dose for a nasopalatine block?

A

Until tissue blanches

27
Q

What does the greater palatine block anaesthetise?

A

Posterior portion of the hard palate both hard and soft tissues distal to the canines and medial to midline

28
Q

What are the landmarks for the greater palatine block?

A

Greater palatine foramen

29
Q

What is the injection site for a greater palatine block?

A

Soft tissue just anterior to the depression created by the greater palatine foramen, usually distal to the upper 2nd molar but it can be more anterior

30
Q

What is the dose for a greater palatine block?

A

Up to 1/2 cartridge

31
Q

What does an ID block anaesthetise?

A

All teeth in the quadrant, buccal soft tissues from mental nerve to midline, tongue and lingual soft tissues

32
Q

How long is a blue needle?

A

2.5cm

33
Q

How long is a yellow needle?

A

3.5cm

34
Q

What is the dose for an ID block?

A

1 cartridge

35
Q

What is the dose for mental block?

A

No more than 2/3 cartridge

36
Q

What does the long buccal block anaesthetise?

A

Soft tissues and periosteum buccal to the Mandibular molars

37
Q

What are the landmarks for a long buccal block?

A

Mandibular molars and the mucobuccal fold

38
Q

What is the injection site for long buccal block?

A

Distal and buccal to the most distal molar in the arch on the anterior border of the ramus

39
Q

What is the dose for a long buccal block

A

No more than 1/2 cartridge

40
Q

What are analgesics?

A

Pain reliever or pain killer

41
Q

What is Trigeminal neuralgia?

A

Sudden, severe facial pain - often described as a sharp, shooting pain
Thought to be caused by compression of the Trigeminal nerve

42
Q

What is local anaesthetic?

A

Drug that causes reversible local anaesthesia and loss of nociception (the neural processes of encoding and processing noxious stimuli)

43
Q

How do LAs work with impulse conduction?

A

They reversibly block impulse conduction along nerve axons and other excitable membranes that use sodium channels as the primary means of action potential (nerve impulse) generation

44
Q

What are some ideal properties of LA?

A

Stable in solution, non-irritating to tissues, no permanent damage to nerves, no systemic toxicity, no allergic response, potent, rapid onset of action, predictable duration of action, sensory > motor, no active metabolites

45
Q

What are the 2 main groups of LA

A

Amide and esters

46
Q

What is the mechanism of action of LA? What are they trying to target?

A

Trying to target sodium or ion channels

47
Q

How does LA work (in terms of Na+ ion channels)?

A

In order for voltage gated sodium channels to open is a change in voltage
LA passes through the cell membrane through the cytoplasm to the binding site
LA inhibits the influx of Na into the neurone (by blocking sodium channels) which means action potential (nerve impulses) cannot arise and signal conduction is inhibited.
Because the signal does not get passed to the brain, the pt can’t detect the firing

48
Q

What is the order of sensitivity to LA inhibition?

A

Autonomic > cold > warmth > pain (first pain is A(alpha) fibres, then C fibres) > touch > deep pressure

49
Q

How does inflammation reduce the action of LA?

A

Inflammation can cause acidosis which is an increased acidity of the blood plasma (acidosis is when arterial pH falls below 7.35)
Most of the anaesthetic is ionised and therefore, unable to cross the cell membrane to reach its cytoplasmic-facing site of action on the sodium channel
- Only non-ionised LA diffuses readily across cell membrane and being ionised (in acidic conditions) does not allow it to reach the binding site on the intracellular portion of the sodium channel

50
Q

What type of pain presents with c fibres?

A

Dull, long lasting

51
Q

What type of pain is presented with A(alpha) fibres?

A

Short, sharp pain

52
Q

What does anaphylactic mean?

A

Allergic reaction

53
Q

Which LAs are amides?

A

Lidocaine, Prilocaine, articaine (contains both ester and amide) bupivacaine, mepivacaine

54
Q

Which LAs are ester based?

A

Benzocaine, procaine, tetracaine

55
Q

What are some examples of LA toxicity?

A

Hypersensitivity (allergic response) or reaction to preservatives
CNS (initial effects are excitatory with involuntary muscle activity; later effect is depressant which may lead to unconsciousness and respiratory arrest
Cardiac (possible reduction in cardiac output may lead to circulatory collapse)

56
Q

Why is LA often given with vasoconstrictors?

A
  • prolongs action
  • reduces plasma levels (less risk of CNS effects)
  • greater anaesthesia or reduced dose
57
Q

What are some reasons for failure of LA?

A

Insufficient solution injected
Inaccurate placement
Intravascular injection
Biological variation
Anatomical variation
Infection or inflammation

58
Q

What kinds of symptoms with allergy to LA?

A

Swelling
Nausea malaise
May lose consciousness
Facial and laryngeal oedema (swelling)

59
Q

What do you do in a vasovagal attack? (Faint)

A

Lie flat (head down)
Loosen tight clothing
Call for help
Glucose drink
Check airway, breathing, circulation
Oxygen if necessary
If not recovered in 2-3mins assume not a simple faint

60
Q

What are the drug interactions with adrenaline?

A

Interactions with antidepressants MAOIs (possibly tricyclics)
Care in hypotension and heart problems (especially if condition is unstable)

61
Q

What are the drug interactions with felypressin

A

DO NOT use in pregnancy