Loa loa Flashcards
The African eye worm
Loa loa
Size of adult female loa loa
40-70 mm x 0.45-0.60 mm
Size of male in loa loa
at 30-34 mm x 0.35-0.40 mm
The vector for L. loa filariasis are flies from two species of the genus?
The genus Chrysops,C. silacea and C. dimidiata
What is the infect stage Loa loa?
3rd larvae .
The larvae develop into adults that commonly reside?
subcutaneous tissue
Loa loa During the day they are found in
peripheral blood,
During noncirculation phase they found in
Lung
the microfilariae lose their sheaths and migrate from
the fly’s midgut through the hemocoel to the thoracic muscles of the
arthropod after?
ingestion
What is The most common pathological squeal associated with L. loa
infections
Calabar or Fugitive swellings
Infections in nonresidents were more often symptomatic. They have
frequently reoccurring episodes of severe angioedema, increased in what?
level of IgE, and very high antibody titers
What is the Complications of loa loa
renal disease, encephalopathy, and cardiomypathy
What is Diagnosis bassed in clinical history
Calabar swellings, worm migration through the
eye, eosinophilia, residence in endemic area)
Identification of the microfilariae of loa loa
blood smear thick or thin and stained with Giemsa or
hematoxylin-and-eosin.
For increased sensitivity, concentration techniques
can be used( centrifugation of the blood sample lysed in 2%
formalin (Knott’s technique), or filtration through a polycarbonate
membrane ( Nucleopore filtration)
The sheathed microfilariae must be differentiated from
W. bancrofti
and B. malayi
