LO6 Wound Care Flashcards
4 stages of wound healing
- Hemostasis
- inflammation
- proliferation
- maturation
hemostasis stage of healing
Hemostasis is characterized by clot formation resulting in cessation of bleeding.
This process is enhanced by a 5–10 minute phase of vasoconstriction.
Medical conditions or medications that alter the body’s ability to clot will slow down the initiation of healing.
inflammation stage of healing
This is the body’s defense mechanism against bacterial invasion.
Neutrophils and monocytes are attracted at the same time to the wound site
the later phases of inflammation are characterized by conversion of monocytes to macrophages.
Any medical conditions (autoimmune diseases) or anti-inflammatory medications will alter this phase and delay healing.
Neutrophils
migrate through the blood vessels to accumulate in the periphery of the wounded tissue.
The main function of these cells is to phagocytose local bacteria and debris
Macrophages
continue the process of phagocytosis
proliferation stage of healing
The phase of proliferation overlaps inflammation.
The key cells of this phase of healing are the fibroblasts and myofibroblasts.
fibroblasts and collagen synthesis
Fibroblasts secrete a loose extracellular matrix that is rich in collagen.
Collagen synthesis peaks 5–7 days post injury.
Wound contraction
is the reduction of a tissue defected by the centripedal movement of the surrounding skin.
This process of contraction will peak at approximately two weeks after the injury and varies in its ability to reduce wound size by the depth of the wound and the tension of the surrounding tissue.
Angiogenesis
the formation of new blood cells occurs simultaneously with the above two cellular processes.
This is the process where capillaries bud from pre-existing small vessels found in close proximity to the wound to form granulation tissue.
maturation stage of wound healing
Remodeling of the immature tissue occurs at the same time as granulation tissue formation.
This process occurs for a period of months or years after initial wound closure
Factors Affecting Wound Healing
Metabolic Disorders Nutrition Medications Ischemia Infection Treatment regimes Psychosocial well being Aging Smoking
Sanguineous fluid
blood, hemorrhage
Fresh—bright red
Old—dark brown
Serous fluid
clear, light, straw-colored
Serosanguineous fluid
clear, pinkish color
Purulent
thick, curdy, yellow, green, white, foul-smelling “pus”