LO2 - Detox & Withdrawal Flashcards
Withdrawal is..
The longer the drugs half life, the longer the withdrawal symptoms
General depression is a symptom
Withdrawal for sedatives, hypnotics and anxiolytics
Peak at 24 hours
Lasts up to 1 week
Withdrawal for lorazepam and oxazepam
6 to 8 hours after ended
Withdrawal for diazepam
Not developed for a week or two
Withdrawal decreases after 3 to 4 weeks
15 mg can cause withdrawal
Higher doses can cause seizures or delirium
Withdrawal for alcohol
Onset is 6 to 24 hours
Lasts 3-5 days
Symptoms o alcohol withdrawal
Autonomic hyperactivity - sweating, pulse above 100 bpm
Hand tremor
Insomnia
Nausea/vomiting
Hallucinations
Psychomotor agitation
Anxiety
Tonic-clonic seizures
Alcohol withdrawal medical emergencies
Disorientation
Delusions
Visual hallucinations
Seizures
Wernickes symptoms
Ataxia - uncoordinated
Eye abnormalities
Mortality rate of 15-20%
Korsakoff symptoms
Amnesia
Neurocognitive disorder (thiamine deficiency)
Korsakoff symptoms
Amnesia
Neurocognitive disorder (thiamine deficiency)
Detoxification definition
Early treatment stage
Body eliminates the substance
Initial and immediate goal to have meds alleviate unpleasant withdrawal symptoms
3 strategies for detoxification
Agonist or substation therapy -used to induce cross tolerance to substance
Antagonist therapy - produce extinction by preventing user from experiencing the reinforcement effect
Aversion therapy - produce adverse reaction following ingestion
Meds that and in alcohol withdrawal
Benzos
Barbiturates
Beta-blockers
Antabuse
Stimulant withdrawal symptoms
Fatigue
Vivid, unpleasant dreams
Insomnia or hypersernia
Increased appetite
Psychomotor agitation or retardation
Tobacco withdrawal symptoms
Irritability, frustration, anger
Anxiety
Difficulty concentration
Increased appetite
Restlessness
Depressed mood
insomnia