LM Intro Key Flashcards
1
Q
Describe the INTERSTROKE study
Context: How risk factors from unhealthy behaviours influence health outcomes
BR 22
Yusuf S,Lancet 2016:388(10046)761-775.
A
Design: International case-control study
Population: 26,919 subjects (13,447 with stroke [ischemic & hemorrhagic], 13,472 controls) with acute first stroke.
- from 32 countries in Asia, American, Europe, Australia, Middle East, Africa
- Looked at odds ratios of multiple risk factors for stroke and population attributable risk (PAR).
- all 10 risk factors account for 90% of PAR in men & women.
- similar associations noted in men/women, old/young, all regions of the world.
Mnemonic: ESCAPED
E - Exercise
S - Smoking
C - CV - Htn, lipids, cardiac (afib)
A - Alcohol
P - Stress
E - Endo - DM, waist-hip ratio
D - Diet
