Living with T1D

Question 1

What affect does exercise have on control of blood glucose?

Answer 1

• Increases glucose uptake into muscle
• After vigorous exercise, muscle continues to take up glucose to replenish stores (glycogen)
• Stress releases adrenaline + cortisol > increasing BG

Question 2

What does pancreas release insulin depending on?

Answer 2

Portal vein glucose

Question 3

What exaggerates insulin response after a meal?

Answer 3

Incretins

Question 4

What are the effects of incretins?

Answer 4

e. g. GLP-1
- Reduces B cell workload by increasing B cell response
- Enhances glucose-dependent insulin secretion

Question 5

What are the different ways to deliver inslulin?

Answer 5

• I.V - only lasts minutes (continuous IV = risk of sepsis)
• I.M - works quickly + lasts longer but difficult to self administer
• S.C - slower but safer from LT use
• Portal vein delivery not practical

Question 6

Which insulin regime’s are used in T1D?

Answer 6

• x 2 daily free mix
• x 2 daily premixed
• Basal bolus regime
• Insulin pump therapy