Liver transplant

Question 2

Reasons for liver transplant

Answer 2

1. Chronic liver disease - cirrhosis, viral hepatitis, autoimmune/idiopathic liver disease
2. Paracetamol poisoning

Question 3

Assessing for need for transplant

Answer 3

Model for End Stage Liver Disease
Blood tests - ALT, AST, ALP, bilirubin, albumin, INR

Question 4

Contraindications

Answer 4

poor cardiac reserve, comorbidities, failure to abstain from alcohol

Question 5

Management

Answer 5

Immunosuppression:
Calcineurin inhibitors (tacrolimus, ciclosporin)
Azathioprine
Steroids