Liver Transplant

Question 1

What are the clinical features of liver transplant?

Answer 1

Mercedes-Benz or Roof-top scar
Signs of chronic liver disease

Question 2

What are the indications for liver transplant? (3)

Answer 2

1. Cirrhosis
2. Acute hepatic failure (hep A, B and paracetamol overdose)
3. Hepatic malignancy

Question 3

What are the success rates for liver transplant?

Answer 3

80% 1 year
70% 5 year
56% 15 year

Question 4

What are the King’s College criteria for liver transplant?

Answer 4

pH <7.3
INR >6.5
Cr >300
Encephalopathy II or III

Question 5

What are some varient reasons for liver transplant? (6)

Answer 5

1. Diuretic resistant acites
2. Chronic hepatic encephalopathy
3. Irretractable pruritis
4. Hepatorenal syndrome
5. Polycystic liver disease
6. Recurrent cholangitis

Question 6

What are the contrandications for liver transplant? (4)

Answer 6

1. IVDU
2. Excess alcohol
3. Medical/psychiatric comorbidities
4. Malignancy

Question 7

What is in the UKELD score? (4)

Answer 7

1. INR
2. Creatinine
3. Bilirubin
4. Sodium

Score >49 means eligible for transplant

Question 8

What are the immunosuppresants for liver transplant? (4)

Answer 8

1. Tacrolimus - causes tremor
2. Aziothioprine
3. Mycophenilate
4. Cyclosporin - gum hypertrophy

Question 9

What are the side effects of immunosupression therapy in liver transplant? (2)

Answer 9

1. Skin lesions
2. Diabetes