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Clinical Pathology > Liver & Other Enzymes Test > Flashcards

Liver & Other Enzymes Test Flashcards

1
Q

Aspartate Aminotransferases is aka

A

SGOT- Serum Glutamic Oxaloacetic Transaminase

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2
Q

Alanine Aminotransferase is aka

A

SGPT- Serum Glutamic Pyruvic Transaminase

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3
Q

more specific in detecting non-alcoholic asymptomatic patients; dx of acute hepatitis

A

ALT

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4
Q

Used to monitor therapy of potentially hepatotoxic drugs; dx of chronic hepatitis

A

AST

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5
Q

Normal De Ritis Ratio

A

< 1.0

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6
Q

If the De Ritis Ratio is <1

A

acute viral hepatitis

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7
Q

If De Ritis Ratio >1.0 but <2.0

A

cirrhosis and non-viral hepatitis

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8
Q

If Di Ritis Ratio >2.0

A

Alcoholic liver disease

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9
Q

Normal Value of AST

A

5-30 U/L at 37ºC

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10
Q

Normal Value of ALT

A

6-37 U/L at 37ºC

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11
Q

ALP, 5’NT, LAP, GGT in bone disease

A

Increased, Norma, Normal, Normal

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12
Q

ALP, 5’NT, LAP, GGT in liver disease

A

Increased all

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13
Q

Normal Value of 5’NT

A

2-17 U/L

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14
Q

Normal Value of LAP

A

M: 80-200 U/mL F: 75-185 U/mL

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15
Q

Normal Value GGT

A

M: 0-65 U/L F; 0-45 U/L

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16
Q

What test is used for rape cases

A

Acid Phosphatase

17
Q

Sample of choice in ACP assay

A

Plasma– to minimize platelet effects

18
Q

Normal Value of ACP

A

0-0.8 U/L

19
Q

An assay for GGT which uses p-nitroanilide as substrate

A

Szasz method

20
Q

What hepatitis infection has increased risk for development of HCC

A

HBV or HCV

21
Q

Cholinesterase that is present in serum or plasma

A

Pseudo-cholinesterase

22
Q

Cholinesterase present in RBC and nerve tissues

A

True Cholinesterase

23
Q

When assaying for pseudo-cholinesterase, which is more significant: increase or decrease level

A

Decreased level

24
Q

Decreased CHS is seen in

A

parenchymatous liver disease, acute hepatitis, obstructive jaundice

25
Q

It is a sensitive measure of overexposure to organophosphorus poisoning

A

Pseudo-cholinesterase

26
Q

Normal Value of Cholinesterase

A

4.7-11.8 U/L at 37ºC

27
Q

Normal G6PD

A

220-550 UI/RBC

28
Q

Marker of muscles disease

A

Aldolase (ALS)

29
Q

Increased in metastatic cancer

A

Phosphohexose isomerase (PHI)

30
Q

Increased in primary liver disease, MI w/ CHF. Highest concentration is seen in central veins of liver

A

Isocitrate Dehydrogenase

31
Q

It is decreased in hepatolenticular degeneration (Wilson’s Disease)

A

Ceruloplasmin

Clinical Pathology (2 decks)

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