Liver & Other Enzymes Test

Question 1

Aspartate Aminotransferases is aka

Answer 1

SGOT- Serum Glutamic Oxaloacetic Transaminase

Question 2

Alanine Aminotransferase is aka

Answer 2

SGPT- Serum Glutamic Pyruvic Transaminase

Question 3

more specific in detecting non-alcoholic asymptomatic patients; dx of acute hepatitis

Answer 3

ALT

Question 4

Used to monitor therapy of potentially hepatotoxic drugs; dx of chronic hepatitis

Answer 4

AST

Question 5

Normal De Ritis Ratio

Answer 5

< 1.0

Question 6

If the De Ritis Ratio is <1

Answer 6

acute viral hepatitis

Question 7

If De Ritis Ratio >1.0 but <2.0

Answer 7

cirrhosis and non-viral hepatitis

Question 8

If Di Ritis Ratio >2.0

Answer 8

Alcoholic liver disease

Question 9

Normal Value of AST

Answer 9

5-30 U/L at 37ºC

Question 10

Normal Value of ALT

Answer 10

6-37 U/L at 37ºC

Question 11

ALP, 5’NT, LAP, GGT in bone disease

Answer 11

Increased, Norma, Normal, Normal

Question 12

ALP, 5’NT, LAP, GGT in liver disease

Answer 12

Increased all

Question 13

Normal Value of 5’NT

Answer 13

2-17 U/L

Question 14

Normal Value of LAP

Answer 14

M: 80-200 U/mL F: 75-185 U/mL

Question 15

Normal Value GGT

Answer 15

M: 0-65 U/L F; 0-45 U/L

Question 16

What test is used for rape cases

Answer 16

Acid Phosphatase

Question 17

Sample of choice in ACP assay

Answer 17

Plasma– to minimize platelet effects

Question 18

Normal Value of ACP

Answer 18

0-0.8 U/L

Question 19

An assay for GGT which uses p-nitroanilide as substrate

Answer 19

Szasz method

Question 20

What hepatitis infection has increased risk for development of HCC

Answer 20

HBV or HCV

Question 21

Cholinesterase that is present in serum or plasma

Answer 21

Pseudo-cholinesterase

Question 22

Cholinesterase present in RBC and nerve tissues

Answer 22

True Cholinesterase

Question 23

When assaying for pseudo-cholinesterase, which is more significant: increase or decrease level

Answer 23

Decreased level

Question 24

Decreased CHS is seen in

Answer 24

parenchymatous liver disease, acute hepatitis, obstructive jaundice

Question 25

It is a sensitive measure of overexposure to organophosphorus poisoning

Answer 25

Pseudo-cholinesterase

Question 26

Normal Value of Cholinesterase

Answer 26

4.7-11.8 U/L at 37ºC

Question 27

Normal G6PD

Answer 27

220-550 UI/RBC

Question 28

Marker of muscles disease

Answer 28

Aldolase (ALS)

Question 29

Increased in metastatic cancer

Answer 29

Phosphohexose isomerase (PHI)

Question 30

Increased in primary liver disease, MI w/ CHF. Highest concentration is seen in central veins of liver

Answer 30

Isocitrate Dehydrogenase

Question 31

It is decreased in hepatolenticular degeneration (Wilson’s Disease)

Answer 31

Ceruloplasmin