GI Disorders Diagnostic Test Flashcards
Diarrheal Disease: isotonic stool, persist during fasting
Secretory Diarrhea
Diarrheal Disease: occur w/ lactase deficiency, d/t osmotic forces exerted by unabsorbed luminal solutes, abates w/ fasting
Osmotic Diarrhea
Diarrheal Disease: inadequate nutrient absorption, associated w/ steatorrhea, relieved by fasting
Malabsorbtive Diarrhea
Diarrheal Disease: d/t inflammatory disease, purulent, bloody stools, continue during fasting
Exudative Diarrhea
important enzymes in breakdown of disaccharide in SI
lactase-phlorizin hydrolase, sucrase isomaltase, maltase-glucoamylase
Secondary disaccharide deficiency can be caused by what drugs
neomycin, kanamycin, methrotrexate
Most important cause of nosocomial diarrhea (antibiotic-associated diarrhea)
Clostridium difficile
Clostridium difficile characteristic
gram positive, spore-forming, anaerobic bacillus
Clinical Manifestation of antibiotic-associated diarrhea
mild, watery diarrhea; pseudomembranous colitis; toxic megacolon; lead to colonic perforation & peritonitis
Patient presentation of antibiotic-associated diarrhea
watery diarrhea, abdominal pain/cramping, fever, malaise, occult GI bleeding
Irrespective of the cause, what is the most common feature of malabsorption syndrome
diarrhea (especially steatorrhea)
Screening Test for Steatorrhea
Micro exam for fat globules & serum carotenoid determination
Major precursor of Vitamin A in human
Carotenoid
What might cause a low level of serum carotenoid
Liver disease & high fever
Elevated serum carotenoid are seen in patients
Hypothyroidism, diabetes, hyperlipidemia, excessive intake of carotene