GI Disorders Diagnostic Test Flashcards
Diarrheal Disease: isotonic stool, persist during fasting
Secretory Diarrhea
Diarrheal Disease: occur w/ lactase deficiency, d/t osmotic forces exerted by unabsorbed luminal solutes, abates w/ fasting
Osmotic Diarrhea
Diarrheal Disease: inadequate nutrient absorption, associated w/ steatorrhea, relieved by fasting
Malabsorbtive Diarrhea
Diarrheal Disease: d/t inflammatory disease, purulent, bloody stools, continue during fasting
Exudative Diarrhea
important enzymes in breakdown of disaccharide in SI
lactase-phlorizin hydrolase, sucrase isomaltase, maltase-glucoamylase
Secondary disaccharide deficiency can be caused by what drugs
neomycin, kanamycin, methrotrexate
Most important cause of nosocomial diarrhea (antibiotic-associated diarrhea)
Clostridium difficile
Clostridium difficile characteristic
gram positive, spore-forming, anaerobic bacillus
Clinical Manifestation of antibiotic-associated diarrhea
mild, watery diarrhea; pseudomembranous colitis; toxic megacolon; lead to colonic perforation & peritonitis
Patient presentation of antibiotic-associated diarrhea
watery diarrhea, abdominal pain/cramping, fever, malaise, occult GI bleeding
Irrespective of the cause, what is the most common feature of malabsorption syndrome
diarrhea (especially steatorrhea)
Screening Test for Steatorrhea
Micro exam for fat globules & serum carotenoid determination
Major precursor of Vitamin A in human
Carotenoid
What might cause a low level of serum carotenoid
Liver disease & high fever
Elevated serum carotenoid are seen in patients
Hypothyroidism, diabetes, hyperlipidemia, excessive intake of carotene
Used in the diagnosis of celiac disease (gluten-sensitive enteropathy)
cellobiose-mannitol sugar permeability test & lactulose-mannitol test
Used to asses function of terminal ileum, for Vitamin B12 absorption
Schilling test
Fecal elactase should only be performed in what kind of stool
formed stool
Munchausen’s syndrome by proxy
adults administered laxatives surreptitiously to young children
What are colonic stimulants that are abused
Senna, aloin, cascara