Liver function tests Flashcards
1
Q
What two markers can be used to indicate obstructive or cholestatic liver disease
A
ALP
GGT
2
Q
What are high ALT and AST levels generally indicative of?
A
Hepatocellular damage
3
Q
What would an elevated bilirubin be indicative of?
A
Obstruction to bile flow
4
Q
What is the most sensitive LFT for hepatocellular damage
A
ALT
5
Q
What are ALP and GGT and where are they primarily located
A
Enzymes found mainly in the bile ducts of the livger
6
Q
What happens to the prothrombin time in liver disease and why
A
It becomes prolonged due to diminished synthesis of clottting factors
7
Q
What happens to albumin in chronic liver disease
A
Decreases