Cirrhosis Flashcards
give the two most common causes of cirrhosis
chronic alcohol abuse
Hep B and C
give three drugs that can cause cirrhosis
amiodarone
methotrexate
methyldopa
what causes leuconychia
hypoalbuminaemia
give some things you might find on examination of a patient with cirrhosis
spider naevi gynaecomastia ascites loss of sexual hair gynaecomastia xanthelasma ankle oedema liver flap
give the three major complications of cirrhosis
hepatic failure
bleeding oesophageal varices
portal HTN
give some signs of portal HTN
ascites
splenomegaly
caput medusae
what blood results might you see in cirrhosis
raised AST, ALT, ALP, yGT
low albumin, WCC and platelets
what investigations should you consider with a patient with cirrhosis
bloods USS MRI ascitic tap biopsy
how do you manage ascites
fluid restriction low salt diet give spironolactone chart daily weight (+ furosemide)
what are the common organisms causing spontaneous bacterial peritonitis
E.coli
klebsiella
streptococci
what are the three major signs of decompensated liver failure
jaundice
ascites
encephalopathy
what scoring system do you use to assess prognosis in chronic liver disease
Child-Pugh
what electrolyte abnormality might you see in cirrhosis
hyponatraemia
what procedure can you do in ascites of large volume
if >5L can do a large volume paracentesis
how would you manage oesophageal variceal bleeding
variceal band ligation
