Liver function tests

Question 1

What are the hepatocellular enzymes?

Answer 1

AST –> More acute release

ALT –> More chronic release

Question 2

What are the hepatobilliary enzymes?

Answer 2

ALP and GGT

Question 3

What is Wilson’s disease?

Answer 3

A rare autosomal recessive inherited disorder of copper metabolism that is characterised by excessive deposition of copper in the liver, brain, and other tissues.

Decreased caeruloplasmin helps to diagnose wilson’s disease and/or copper deficiency.

Question 4

Deficiency of a1-antitrypsin indicates….

Answer 4

Lung or liver disease.

Question 5

High AFP (a-fetoprotein) levels indicate….

Answer 5

Liver cancer

Question 6

What is haemochromatosis?

Answer 6

Overload of iron in the body.

Question 7

What is the expected AST:ALT ratio?

Answer 7

O.8

> 1.0 indicates liver cirrhosis

Question 8

What are the main causes of acute hepatocellular damage?

Answer 8

Ischaemia
Chemicals
Drugs
Acute hepatitis

Question 9

What is ELF test?

Answer 9

Enhanced Liver Fibrosis test is used to assess liver fibrosis severity.

Blood test that measures HA, P3NP, TIMP.

> 9.8 is severe