Liver Disorders in Pregnancy

Question 1

Physiological changes in pregnancy related to the liver

Answer 1

**Increase
**Liver metabolism
ALP increases 2-4 fold (placental production)

**Decrease
**Albumin

Any abnormality in bilirubin or transaminases needs further evaluation
Earlier in pregnancy the abnormality presents -> more likely is it due to pre-existing liver disease or non-pregnancy related disease