Liver Disorders

Question 1

What is meant by cholestasis

Answer 1

Impaired bile formation or flow - causes fatigue, pruitus (itching), dark urine, pale or jaundice

Question 2

How can cholestasis be relieved

Answer 2

Can be relieved by cholestyramine, ursodeoxycholic acid, rifampicin

Question 3

How do you manage cholestasis in pregnancy

Answer 3

Intrahepatic cholestasis in pregnancy
During late pregnancy- adverse fetal outcomes
Treatment of pruitus associated - ursodeoxycholic acid

Question 4

What is meant by gallstones

Answer 4

Hard minerals or fatty deposits forming stones in the gallbladder bile duct

Question 5

What are the different types of gall stones

Answer 5

Majority of patients : asymptomatic
Irritated/ blocked gallbladder = pain, infection and inflammation
- if left untreated = complications (biliary colic, cholecystitis, cholangitis, pancreatitis)

If symptoms develop - surgically removed

Question 6

What is the drug treatment for gall stones

Answer 6

Mild- moderate pain: paracetamol or NSAID
Severe pain: IM diclofenac