Liver Diseases Flashcards
Serum Ascites Albumin Gradient < 1.1g/dl
Infection
Cancer
Nephrotic Syndrome
Serum Ascites Albumin Gradient >1.1g/dl
Portal HTN
CHF
Hepatic Vein Thrombosis
Constrictive Pericarditis
Best initial Test for Spontaneous Bacterial Peritonitis
Cell Count with >250 Neutrophils
Most accurate test for Spontaneous Bacterial Peritonitis
Fluid Culture
Treatment for Spontaneous Bacterial Peritonitis
Cefotaxime
Ceftriaxone
Labs in Acute Alcoholic Hepatitis
AST>ALT
Increased GGTP
Increased Bilirubin
Increased INR
Increased PT
If Discriminate Factor >32 in Acute Alcoholic Hepatitis
Treat with Steroids
How to calculate Discriminate Factor
4.6(Patients PT-Control PT) + Bilirubin
Most accurate test for Primary Biliary Cholangitis (PBC)
Liver biopsy
Most accurate blood test for Primary Biliary Cholangitis (PBC)
Anti-mitochondrial Ab
Treatment for Primary Biliary Cholangitis (PBC)
Ursodeoxycholic Acid and Obeticholic Acid
-decrease Fibrosis
Most accurate Test for Primary Sclerosing Cholangitis (PSC)
MRCP or ERCP
-beeding, narrowing obstruction in biliary system
Best initial treatments in Primary Sclerosing Cholangitis (PSC)
Ursodeoxycholic acid
Try to dilate strictures
Best initial Test to diagnose Hemochromatosis
Iron Study
-Increase Serum FE
-Increased Ferritin
-Decreased Iron Binding capacity
Most accurate test for Hemochromatosis
Liver biopsy for Increased Iron
Best initial Test for Hepatitis
Hep A,C,D,E IgM Ab
-Acute infection
Hep A,C,D,E, IgG Ab
-resolution of acute infection
Treatment for Hemochromatosis
Phlebotom
Iron Chelation
-Deferasirox
-Deferiprone
-Deferoxamine
Other Tests for Hepatitis
Increased Direct Bilirubin
Increased ratio of ALT:AST
Increased Alkaline Phosphatase
PCR for Viral Load
-Hep B,C
Diagnosis for Wilson Disease
Slit Lamp Exam
-Keyser-Flescher Rings
Urine
-increased Copper
Low Ceruloplasmin
Liver Biopsy
-Increased Hepatic Copper
Treat Wilson Disease
Penicillamine
Most accurate test for autoimmune Hepatitis
Liver Biopsy
Antibodies in autoimmune hepatitis
Anti-smooth muscle
Treatment for autoimmune Hepatitis
Prednisone
Azathoprine
Most accurate test to diagnose Non-alcoholic fatty liver disease
Biopsy
Treatments for Non-Alcoholic Fatty Liver Disease
Correct Risk factors
Vitamin E
Pioglitazone
-if NASH and DM
Focal Nodule Hyperplasia
Central Scarring
no malignant potential
Hemangioma
Tuft of abnormal vessels
Imaging is diagnostic
No malignant potential
Hepatic Adenoma
Grows with estrogen
Large may rupture
small malignant potential
