Liver and Biliary system

Question 1

Increased serum levels of unconjugated bilirubin–exceeding capacity of hepatocyte to conjugate bilirubin?

Answer 1

Autoimmune hemolytic anemia

Question 2

These pathological changes are seen in what disease

• Disarray of liver cell plates
• Ballooning degeneration of hepatocytes
• Intracellular and extracellular bile stasis
• Apoptotic (councilman) bodies
• Mononuclear inflammatory cell infiltrates

Answer 2

Acute viral hepatitis

Question 3

What are the 4 extra hepatic ailments that can be seen with HBV carriers?

Answer 3

Serum sickness-like syndrome
Glomerulonephritis
Cryoglobulinemia
Polyarteritis nodosa

Question 4

Anti-mitochondrial antibodies?

Answer 4

Primary biliary cirrhosis

Question 5

Shows substantial fibrosis within the liver, can be confused with metastatic carcinoma, and increased risk in pt exposed to liver fluke C. sinensis and pt with primary sclerosing cholangitis?

Answer 5

Cholangiocarcinoma

Question 6

Sharply demarcated mass that is encapsulated and paler, and associated with oral contraceptive use?

Answer 6

Hepatic adenoma

Question 7

These are characteristic of what?

• Hepatic steatosis
• Hydropic swelling of hepatocytes
• Focal hepatocellular necrosis
• Neutrophilic infiltration
• Cytoplasmic hyaline inclusions within hepatocytes–mallory bodies

Answer 7

Acute alcoholic hepatitis

Question 8

Presents with fatigue, anorexia, jaundice, xanthomas and pruritus–hypercholesterolemia and is associated with antimitochondrial antibodies?

Answer 8

Primary biliary cirrhosis

Question 9

Increased incidence of cirrhosis and hepatocellular carcinoma and stains with prussian blue?

Answer 9

Hereditary hemochromatosis

Question 10

Occlusion of the hepatic veins and their tributaries caused by thrombosis?

Answer 10

Budd-chiari syndrome

Question 11

Pts with HBV are at 200 fold increase of developing______.

Answer 11

Hepatocellular carcinoma

Question 12

Characterized by inflammation and obliterative fibrosis of intrahepatic and extra hepatic bile ducts with dilation of preserved segments–beaded appearance. Is associated with ulcerative colitis.

Answer 12

Primary sclerosing cholangitis

Question 13

What is a late complication of Primary sclerosing cholangitis?

Answer 13

Cholangiocarcinoma

Question 14

Benign condition with liver biopsy showing accumulation of coarse, iron-free, dark brown granules in hepatocytes and Kupffer cells?

Answer 14

Dubin-Johnson syndrome

Question 15

Deficiency of glycogen-branching enzyme–leading to accumulation of amylopectin in the liver, muscle, and other tissues?

Answer 15

Anderson disease