Liver Flashcards
best test for vit k def and warfarin therapy
PT
Useful in determining liver faulure; shortest half life
Factor VIII
AST: ALT ratio
> 2:1
more specific for liver disease
ALT
Elevations point to extrahepatic causes
obstructive cholestasis
direct (conjugated bilirubin)
elevations point to intrahepatic cholestasis; hemolytic d/o
indirect (unconjugated bilirubin)
indicative of biliary obstruction
ALP
early marker and sensitive test for hepatobiliary disease
GGTP
JAUNDICE IS DETECTABLE WHEN SERUM BILIRUBIN IS MORE THAN ___
2.5-3 mg/dL
central arteriole with tiny radiating vessels, mainly on trunk and face
spider angiomata
cause of spider angiomata
elevated estradiol
decreased estradiol degradation in the liver
prominent veins radiating from umbilicus
caput medusae
epigastric vascular murmur
cruveilhier- Baumgarten syndrome
erythema sparing central portions of the palm
palmar erythema
cause of palmar erythema
inc estradiol
dec estradiol degradation in the liver
sweet pungent smell n liver failure
fetor hepaticus
spontaneous bacterial peritonitis
neutrophil count more than ___
250/ml
culture positive community acquired SBP
e. coli
culture positive nosocomial SBP
strep enterococcus
tx SBP
1ST line- cefotaxime
co- amox, quinolones
predicts the surgical risk of intra abdominal operations performed in px wth cirrhosis
child-turcotte-pugh score
normal portal pressure
5-10 mmhg
direct portal venous pressure >5mmhg of IVC pressure
splenic pressure more than 15
portal htn
pressure necessary for varices to form and bleed
> 12mmhg
most accurate method of determining portal htn
hepatic venography
most significant manifestation of portal htn
esophageal varices ( left gastric vein)