lipids Flashcards

1
Q

how do you classify a lipid?

A

molecules which are soluble in organic solvents and insoluble in water
they form aggregates held together by weak interactions

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2
Q

what are the 4 functions of lipids?

A

structural component of membrane
intracellular storage depots of metabolic fuel
protection

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3
Q

what are the simplest lipids?

A

fatty acids

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4
Q

which end do you start numbering the carbons in a fatty acid?

A

from the carboxyl group end

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5
Q

what are examples of saturated fatty acids?

A

palmitic acid

stearic acid

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6
Q

what is an example of an unsaturated fatty acid?

A

oleic acid

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7
Q

what is the relationship between chain length and melting point?

A

as the chain lengthens, the melting point increases

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8
Q

how many isomeric forms can molecules that contain double bonds occur in?

A

two

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9
Q

what two isomeric forms can molecules containing double bonds occur in?

A

cis

trans

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10
Q

what are cis isomers?

A

similar groups are on the same side of the double bond

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11
Q

what are trans isomers?

A

similar groups are on opposite sides of the double bond

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12
Q

what does amphipathic mean?

A

part of the molecule is hydrophobic and part is hydrophilic

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13
Q

what is the relationship between the number of double bonds and the degree of curve of the chain?

A

the more double bonds the more curve

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14
Q

what angle does a double bond create in a chain?

A

30 degree

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15
Q

what is an acylglycerol?

A

esters of fatty acids with a sugar alcohol called glycerol derived from glyceraldehyde

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16
Q

what is a triacylglycerol?

A

an acylglycerol with 3 fatty acids

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17
Q

what is a diacylglycerol?

A

an acylglycerol with 2 fatty acids

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18
Q

what is a monoacylglycerol?

A

an acylglycerol with one fatty acid

19
Q

what is the function of triacylglycerols?

A

storage of metabolic fuels

20
Q

are triacyglycerols amphipathic?

21
Q

how are fatty acids broken down?

A

beta oxidation

22
Q

what makes triacylglycerols good for storage?

A

uncharged
neutral
compact

23
Q

what are adipocytes?

A

fat storage cells

24
Q

what is hydrogenation?

A

an industrial process which saturates the double bonds in an oil and solidifies it using hydrogen and a catalyst

25
what is liquefaction?
the opposite of hydrogenation | when hard fats are exposed to air and are oxidised and double bonds are formed
26
what are waxes?
similar to triacylglycerols but they are esters of long chain fatty acids with long chain monohydroxylic alcohols
27
what is the function of waxes?
external protection
28
what are phospholipids?
more complex lipids similar to acyclycerols but have a hydrophilic phosphate and alcohol group
29
are phospholipids amphipathic?
yes
30
what is the most abundant phospholipid in animal tissue?
phosphatidylcholine
31
what is the parent compound of sphingolipids?
nitrogenous base
32
what is a sphingosine?
a long chain amino alcohol
33
what is a ceramide?
a sphingosine joined to a fatty acid | has two long hydrocarbon tails
34
what are the three different subclasses of sphingolipids?
sphingomyelins cerebrosides gangliosides
35
where are sphingomyelins present?
in membranes | especially myelin sheaths
36
what are cerebrosides?
a sphingolipid and a glycolipid
37
where are gangliosides found?
in cell surface membranes such as in the grey matter of brain tissue
38
what is tay sachs disease?
an inherited condition which impairs the function of the lysosomal enzyme beta HEXA
39
what is the result of the beta HEXA enzyme being impaired?
prevents the breakdown of GM2 ganglioside | it then accumulates to toxic levels which can cause neuron destruction
40
what does tay sachs disease cause?
retarded development paralysis blindness death by the age of 3 or 4
41
what are isoprenoids?
a class of hydrocarbons which are composed of repeats of the 5 carbon isoprene unit
42
what are eicosanoids derived from?
arachidonic acid
43
what is the role of prostaglandins?
local hormones involved in promoting inflammation
44
what do thromboxanes regulate?
smooth muscle contraction and nerve transmission