Lipids Flashcards

1
Q

What is the definition for lipids

A

Lipids are classified molecules that are insoluble in aqueous solutions and soluble in organic solvents

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2
Q

What are the 4 main functions of lipids

A

STRUCTURAL COMPONENTS of biological membranes
ENERGY RESERVES predominantly in the form of triglycerols
Serve as VITAMINS and MINERALS
LIPOPHILIC BILE SALTS aid in lipid solubilisation

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3
Q

What are the two types of lipids

A

Fatty acids

Cholesterol

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4
Q

What are fatty acids

A

They are long chain hydrocarbon molecules containing carboxylic acid at the end

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5
Q

What does the term saturated mean in relation to fatty acids

A

The hydrocarbon chain contains no double bonds in its main carbon chain

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6
Q

What does the term unsaturated mean in relation to fatty acids

A

That there is a least one carbon double bond in the main hydrocarbo chain

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7
Q

What are the 2 major roles of fatty acids in the body

A

Major component of STORED FAT in the form of triacylglycerols
Components of more complex MEMBRANE LIPIDS

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8
Q

Describe the main structure of triacylglycerides

A

Composed of three fatty acids which are esterified to a glycerol backbone

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9
Q

What reaction occurs when glycerol and three fatty acids join together

A

Condensation to release 3 molecules of water

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10
Q

Describe the structure of phospholipids

A

Glycerol back bone
2 fatty acid chains
One phosphate group

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11
Q

What two things does cholesterol have a role in

A

Has roles in membrane structure

Is a precursor for the synthesis of steroid hormones and bile acids

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12
Q

How is cholesterol transported

A

Via lipoproteins

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13
Q

Why is utilisation and synthesis of cholesterol highly regulated

A

As over accumulation can result in abnormal deposits within the body
For example build up in the coronary arteries can lead to atherosclerosis

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14
Q

Which vitamin is derived from steroids

A

Vitamin D

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15
Q

What does vitamin D regulate

A

Vitamin D steroid hormone regulates gene expression in

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16
Q

What is the biologically active form of vitamin D hormone and what is it’s function

A

1,25- dihydroxy vitamin D3

Its function is to regulate calcium and phosphorous homeostasis

17
Q

What are the 4 main steroid hormones

A

Pregnenolone
Estradiol
Testosterone
Progesterone

18
Q

Where is pregnenolone produced

A

Produced directly from cholesterol

19
Q

What is estrediol and what is it’s role

A

An oestrogen derivative produced in the ovaries

Responsible for secondary female sex characteristics

20
Q

What is progestin and where is it produced

A

Produced directly from pregnendone
Is secreted from the corpus luteum
Responsible for changes in the luteal phase of the menstrual circle

21
Q

What is testosterone and what is it’s function

A

An androgen synthesised in the testies responsive for the secondary male sex characterises