Lipids Flashcards

1
Q

roles of lipids

A

energy storage, structual component of membranes, active roles

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2
Q

why are lipids good storage molecules

A

low oxidation number, low hydration state

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3
Q

fatty acids (general)

A

1) hydrocarbon with carboxylic tail
2) differ in length and degree of saturation
3) usually an even number of C’s

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4
Q

saturated=

A

no double bonds

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5
Q

unstaurated=

A

1 double bond

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6
Q

polysaturated

A

multiple double bonds

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7
Q

where are the double bonds

A

cis configuration and located after carbons 9, 12, 15

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8
Q

what determines fatty acid properties

A

length and degree of saturation

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9
Q

fatty acids with ____ are more liekly to associae than are short chains

A

long chains

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10
Q

fatty acids without ____ are more likely to associate than are with double bonds

A

double bonds

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11
Q

melting temperature of a fatty acid mixture

A

reflects the length and degree of saturation of the hydrocarbon tails, double bonds have a greater influence than the length of the tail

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12
Q

triacylglycerols are the …

A

storage lipids in animals and plants

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13
Q

what does the ester linkage do

A

removes the polar head group to make a more hydrophobic molecule

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14
Q

saponification

A

treatment of animal fat with a strong base will break the ester linkages of triacylglycerols

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15
Q

why are free fatty acids good soaps

A

theyre amphipathic

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16
Q

waxes

A

non-polar esters of long-chain fatty acids and long chain monohydroxylic acids

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17
Q

membrane bilayers of lipids….

A

define cells and regulate the composition of the intracellular environment

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18
Q

component of lipids in membranes

A

two hydrophobic tails and a hydrophilic head group

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19
Q

the most abundant lipids in membranes are

A

glycerophospholipids

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20
Q

what are glycerophospholipids made of

A

glycerol backbone with a phosphate at the C3 position

21
Q

phosphatidate=

A

glycerol-3-phosphate+2 fatty acids

22
Q

plant cells contain

A

galactolipids

23
Q

what are galactolipids made of

A

one or two galactose groups linked to C3 of diacylglycerol

24
Q

what do sulfolipids do

A

provides hydrophilic head

25
spingolipids
derived from sphinigosine, a long chain amino alcohol
26
three classes of sphingolipids
1) aphingomyelins 2) cerbrosides 3) Gangliosides
27
what are sphingomyelins
contain phosphocholine or phosphoethanolamine
28
what are cerebrosides
glycossphingolipid
29
gangliosides
1) glycosphinilpid 2) more than 6 sugar units, many variations 3) contain N-acteylneuraminic acid (Sialic Acid)
30
where are phospholipids and sphingolipids degraded
lysosmes
31
what do the membrane lipids of extrmophiles (archaebateria) contain
long chain hydrocarbons linked at either end to glycerol through stable ether linkages
32
what are sterols
are structural membrane lipids and serve as precursors for many biologically active products
33
what do steriods contain
four fused ring systems: 3-six carbon rings (A,B,C) and a 5carbon D ring (rigid and planar)
34
what does choloestrol do
mediating membrane fluidity nad serving as a precursor of the steriod hormones and bile salts
35
what are active roles for the lipids
1) Intracellular signalling molecules 2) hormones 3) enzyme cofactors 4) pigments 5) vitamins
36
Eicosaniods
paracrine hormones (act on cells near point of production)
37
three classes of Eicosaniods
1) Prostaglandins 2) thromboxanes 3) Leukotrienes
38
Prostaglandins
constriction of blood vessels (fever, inflammation)
39
Thromboxanes
involved in blood clot formation, also affected by asprin
40
Leukotrines
smooth-muscles contraction/bronchial constriction (asthma)
41
lipid vitamins
A,D,E,K
42
what are vitamins made out of
rings, long alipathic side chains , are hydrophobic
43
Retinal
light-sensitive compund with a role in vision
44
three forms of vitamin A
alcohol (retinol), aldehyde, and retinoic acid
45
where does Vitamin A come from
liver, egg yolks, milk products, or yellow vegtables
46
what does red eye result from
retinal
47
what does vitamin E do
a reducing agent that scavenges oxygen free radicals, may prevent damage to fatty acids in membranes, deficiency causes scaly skin, muscular weakness and sterility
48
what does vitamin K do
required for synthesis of blood coagulation proteins
49
what is warfarin
a viatmin K analog given to patients with excessive blood clotting, also used in rat poison