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Clinical Chemistry Exam 2 > Lipids > Flashcards

Lipids Flashcards

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1
Q

Why are lipids important?

A

-Important constituent of the cell membranes
-Helps in the absorption of fat-soluble vitamins
-Maintains membrane fluidity
-Acts as a thermal insulator and cellular metabolic regulator
-Hormone synthesis
-Organ padding
-Transporters

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2
Q

Fatty Acids

A

-Saturation (one double bond)
-Trans vs cis
-Dietary effects of trans fats
-Synthesis in the body
-Essential fatty acids
-Polyunsaturated (three double bonds)
-Beneficial omega-3

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3
Q

which essential fatty acids are found in plants?

A

Linoleic and linolenic acids

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4
Q

Triglycerides

A

three fatty acid molecules noted by R

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5
Q

Saturated triglycerides includes

A

-No bends in structure, pack tightly
-Solid at RT
-animal sources

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6
Q

unsaturated triglycerides includes

A

-Oil at RT
-Plant sources

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7
Q

What are Phospholipds?

A

-Hydrophilic phospholipid head groups
-amphipathic lipid molecules
-Synthesized in all organs

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8
Q

Define lipid associated terminology

A
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9
Q

Differentiate among structural characteristics of lipids

A
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10
Q

Explain the usefulness of prostaglandins

A
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11
Q

Explain and compare the lipoproteins using the difference in lipid and protein composition

A
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12
Q

Discuss lipid metabolism

A
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13
Q

Explain the lipid pathways; include cell and tissue location

A
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14
Q

For the following pre-analytical variations, recognize and explain the effects of each on serum lipid levels

-Intra-individual variation
-variation due to age, gender, and race
-lifestyle/behavior variations

A
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15
Q

Discuss lipid metabolism in the “fed state” and the “fasting state”

A
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16
Q

Describe the most likely cause, clinical significance, and lipid levels associated with hereditary hypolipidemias

A
17
Q

Explain the cause and/or effect of disorders associated with lipid imbalances

A
18
Q

State the principle of the chemical reaction, sample types required, reference interval, most common interfering substances/source of error, and the usefulness

-Cholesterol methods
-Triglycerides
-LDL methods
-Explain the calculations for LDL
-HDL methods

A
19
Q

Explain the usefulness of apolipoprotein measurements

A
20
Q

Explain the usefulness of patient preparation and the procedure for a fecal fat analysis; include normal and diagnostic levels

A
21
Q

Explain recommended patient preparation protocol, specimen requirements, and abnormal serum appearance when collecting or handling specimens for lipid analysis

A

Clinical Chemistry Exam 2 (3 decks)

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