Lipid Structures Only Flashcards
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Estradiol
z group is just H
Phosphatidic Acid
- z group is ethanol with amine grp
- specifically found on the inner layer of the lipid bilayer
- abundant in brain/nerves
- AKA Cephalin
phosphatidyl ethanolamine
found where?
also called?
9-C16:1
omega-7
Palmitoleic Acid
CH3–(CH2)16–COOH
Stearic Acid
- found in pulmonary surfactant
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phosphatidylglycerol
where is it found?
CH3–(CH2)14–COOH
most common saturated fatty acid in nature
Palmitic Acid
specifically alpha-linolenic, the omega-3 version
9,12,15-C18:3
Linolenic Acid
- found in myelin sheath and other cell membranes
- can also have phosphoethanolamine
(ceramide with a phosphocholine group on the bare OH)
Sphingomyelin
- where are they found?
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Cholesterol
5,8,11,14-C20:4
omega-6 polyunsaturated
- very important as a signaling molecule > creates prostaglandins, thromboxanes, and leukotrienes
Arachidonic Acid
importance?
phosphatidylcholine
AKA lecithin
- main compononents of biological membranes
- glycerol with 2 FAs and phosphate on C3
- glycerol-3-phosphate not 1, because glycerol is prochiral
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What are glycerophospholipids?
Why is the phosphate specifically located on a certain carbon of the backbone?
- serine is Z group
- held on inner layer of cell membrane by flippase
- during apoptosis, flippase stops holding it and its flip to the outer layer to signal macrophages
phosphatidylserine
where is it found?
what does it do?
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Cortisol
9,12-C18:2
omega-6 polyunsaturated
Linoleic Acid
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Testosterone
- inner cell membrane
phosphatidyl-inositol
where is it?
- main constituent of olive oil
9-C18:1
omega-9
Oleic Acid
Cardiolipin
- glycerophospholipid with phosphatidyl-glycerol as its Z group
- in other words 2 phosphatidic acids with glycerol between them
- this means it has 4 FA attached… 2 for each glycerol
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What lipid constitutes about 20% of the inner mitochondrial membrane?
- found in various sphingolipids in cell membranes
- important in signaling as well
(looks like a glycerol with middle OH subbed by amino and 3rd H subbed by 15-C w/ double bond on first C)
Sphingosine
where is it found?
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aldosterone
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Progesterone
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Cholic Acid