Lipid management for the primary and secondary prevention of CVD prevention of Flashcards

1
Q

some essential biological functions of lipids

A

they are a precursor of vitamin D

Steroid hormone precursor

they are used in bile acid synthesis

is a plasma lipoprotein constituent

they aid with membrane fluidity

they insulate nerve fibres

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2
Q

the main classifications of lipoproteins

A

HDL
LDL
IDL(intermediate density lipoprotein)
VLDL
chylomicron and chylomicron remnant

HDLs are the smallest, and the order follows on as listed

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3
Q

out of the classifications of liproteins, which have the largest portions of the following molecules;
proteins
cholesterol
triglycerides

A

HDLs
LDLs
Chylomicrons

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4
Q

what is a healthy cholesterol level

think anout HDL, LDL and total serum cholesterol levels

A

total serum cholesterol should be below 193mg/dL or 5.0mmol/L

LDL cholesterol should be below 116mg/dL or 3.0mmol

HDL cholesterol levels should be above 1.0mmol/L for a man or 1.2mmol/L for a woman/ above 39mg/dL for a man or 46mg/dL for a woman

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5
Q

total cholesterol levels and HDL levels are very sensitive to fasting, true or false

A

false, they are not. therefore they can be used as screening method for CV risk

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6
Q

which lipoprotein classes are recommended for testing while fasting

A

LDLs and triglycerides as they are more affected by fasting

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7
Q

high levels of TG are associated with low levels of ??

A

triglycerides

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8
Q

LDL function

A

LDL release cholesterol into the tissues, including the vessel walls.

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9
Q

what does elevated serum LDL cholesterol indicate?

A

it is a predictor of
cardiovascular disease (CVD) events

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10
Q

HDL function

A

HDL brings cholesterol back from the tissues(like blood vessels) to the liver

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11
Q

what is low serum HDL levels(<1mmol/L) a strong predictor of

A

a strong predictor of
coronary heart disease (CHD)

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12
Q

how does the size of LDLs affect the CHD risk it poses

A

smaller LDLs pose a lower CV risk than larger LDLs. this is because, Small LDL particles are more easily oxidized, making them more likely to trigger inflammation and plaque formation.

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13
Q

Benecheck description

it is the device used commonly in SELFCheck total cholesterol

A

Benecheck is a brand of medical devices that can test blood glucose, cholesterol, uric acid, and more

watch the youtube video on how it works for lipid/ cholesterol testing. the link to the vid can be found on the slides

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14
Q

some non-pharmacological ways to manage or control high cholesterol levels

A

Eating a heart-healthy diet

losing weight

regular exercise

quitting smoking

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15
Q
A
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