Lipid management for the primary and secondary prevention of CVD prevention of Flashcards
some essential biological functions of lipids
they are a precursor of vitamin D
Steroid hormone precursor
they are used in bile acid synthesis
is a plasma lipoprotein constituent
they aid with membrane fluidity
they insulate nerve fibres
the main classifications of lipoproteins
HDL
LDL
IDL(intermediate density lipoprotein)
VLDL
chylomicron and chylomicron remnant
HDLs are the smallest, and the order follows on as listed
out of the classifications of liproteins, which have the largest portions of the following molecules;
proteins
cholesterol
triglycerides
HDLs
LDLs
Chylomicrons
what is a healthy cholesterol level
think anout HDL, LDL and total serum cholesterol levels
total serum cholesterol should be below 193mg/dL or 5.0mmol/L
LDL cholesterol should be below 116mg/dL or 3.0mmol
HDL cholesterol levels should be above 1.0mmol/L for a man or 1.2mmol/L for a woman/ above 39mg/dL for a man or 46mg/dL for a woman
total cholesterol levels and HDL levels are very sensitive to fasting, true or false
false, they are not. therefore they can be used as screening method for CV risk
which lipoprotein classes are recommended for testing while fasting
LDLs and triglycerides as they are more affected by fasting
high levels of TG are associated with low levels of ??
triglycerides
LDL function
LDL release cholesterol into the tissues, including the vessel walls.
what does elevated serum LDL cholesterol indicate?
it is a predictor of
cardiovascular disease (CVD) events
HDL function
HDL brings cholesterol back from the tissues(like blood vessels) to the liver
what is low serum HDL levels(<1mmol/L) a strong predictor of
a strong predictor of
coronary heart disease (CHD)
how does the size of LDLs affect the CHD risk it poses
smaller LDLs pose a lower CV risk than larger LDLs. this is because, Small LDL particles are more easily oxidized, making them more likely to trigger inflammation and plaque formation.
Benecheck description
it is the device used commonly in SELFCheck total cholesterol
Benecheck is a brand of medical devices that can test blood glucose, cholesterol, uric acid, and more
watch the youtube video on how it works for lipid/ cholesterol testing. the link to the vid can be found on the slides
some non-pharmacological ways to manage or control high cholesterol levels
Eating a heart-healthy diet
losing weight
regular exercise
quitting smoking