Lipid lowering agents Flashcards
1
Q
- Cholesterol excreted in bile salts, prevents bile salt reuptake into liver, tricking into believing lower levels
- Low potency, used as adjunct
- Hypercholesterolemia
A
Bile-acid sequestering agents
2
Q
- Inhibits LDL pathway
- High LDL, low HDL
- Not to be used with liver disease, or gout
- Flushing=AE
A
Nicotinic Acid
3
Q
- Inhibits cholesterol catalysis in liver
- Hypercholesterolemia
- Not to be used in pregos/lactators
A
HMG co-A reuctase inhibitors (statins)
4
Q
- Inhibits hepatic TG production, increases HDL production and LDL clearance
- HyperTG
- Hepatic/renal disease contraindication
A
Fibric acid derivatives
5
Q
Can be used for TG
A
Omega-3