Linx Flashcards

1
Q

What factors are associated with the recurrence of reflux symptoms or endoscopic esophagitis in patients on PPIs

A

The functional status of the lower esophageal sphincter (LES) and esophageal body.

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2
Q

What is the recurrence rate of reflux symptoms in patients with both a defective LES and defective esophageal contractions?

A

80%

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3
Q

What is the recurrence rate in patients with a defective LES but normal esophageal contractions?

A

39%

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4
Q

What is the recurrence rate in patients with both a normal LES and normal esophageal contractions?

A

8%

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5
Q

How does gastric distension after meals affect the LES?

A

It can cause effacement (flattening) of the LES, leading to progressive shortening of its length and loss of its competency

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6
Q

What happens to the LES and esophagus due to repeated exposure to gastric juice?

A

The squamous mucosa is destroyed, healing by metaplastic cardiac mucosa, and the LES muscle is permanently damaged, losing length and pressure

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7
Q

What is the concept behind new devices designed to augment LES function?

A

Placing a loose ligature or ring around the inferior border of the LES to prevent its effacement

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8
Q

What is the LINX Reflux Management System?

A

A laparoscopic procedure designed to augment the LES as a functional barrier to reflux without altering the gastric or gastroesophageal junctional anatomy.

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9
Q

How does the LINX device work in relation to the LES?

A

The magnetic attraction between beads prevents LES opening due to effacement and shortening caused by gastric distension

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10
Q

Does the LINX device interfere with swallowing or belching?

A

No, the beads separate to allow food to pass into the stomach and to relieve gastric distension by belching or vomiting

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11
Q

How long does the surgical time for the LINX procedure typically last?

A

Less than 1 hour.

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12
Q

When is the patient typically discharged after the LINX procedure?

A

The same day or, if the procedure is done in the afternoon, the next morning.

instructed to slowly return to a normal diet over the next week

discontinue the use of acid-suppression medication

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13
Q

What is the surgical approach for patients with a hiatal hernia greater than 3 cm?

A

A more extended and less focused dissection is performed to allow the hernia to be dissected and reduced into the abdomen

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14
Q

Who are the ideal candidates for the LINX device?

A

Patients with a partial response to PPIs
those who desire to stop PPI therapy
or those with endoscopic/histologic signs of progression while on PPIs

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15
Q

Is a hiatal hernia a contraindication for the LINX device?

A

No, a hiatal hernia is likely not a contraindication, but long-term data on hiatal hernia recurrence rates are needed

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