lines of defence Flashcards
what are the components of the first line of defence
skin
mucous membranes
normal flora
explain the role of the skin in immune defence
closely packed kerainised skin cells assist in resistance to entry of pathogens.
explain the role of mucous membranes in immune defence
the mucous layers inhibits the entrance of many microorganisms. the mucous traps pathogens before entering the body further.
explain the role of normal flora in immune defence
normal flora suppresses growth of pathogenic bacteria by competing for essential nutrients
state the components of the second line of defence
inflammation
fever
phagocytes and natural killer cutes
protective proteins
describe how inflammation defends us from infection
when cells or tissues are damaged, histamines are released and and triggers vasodilation which causes the heat, redness and swelling. the blood vessels are now more permeable. blood clots form around an abscess to prevent spreading of infection which destroys the agent.
describe how fever defends us from infection
bacterial endotoxins induce fever by stimulating the hypothalamus and release prostaglandins that reset the hypothalamic thermostat of the body.
increased temp=faster reactions.
describe how phagocytes and natural killer cells defends us from infection
phagocytes are a type of white blood cell that is responsible for engulfing and absorbing bacteria and other small cells and particles. natural killer cells are capable of destroying tumour cells.
describe how protective proteins defends us from infection
the complement system is the first part of the immune system that meets invaders like bacteria.
they react directly with antigens and trigger inflammation, attract phagocytes, coat intruder cells to make more appetizing and kill intruders.
what is inflammation and what are some advantages of having an inflammatory response
when cells or tissues are damaged, histamines are released and and triggers vasodilation which causes the heat, redness and swelling. the blood vessels are now more permeable. blood clots form around an abscess to prevent spreading of infection which destroys the agent.
define antibody
a specific protein produces in response to a substance foreign to the body that reacts with the antigen to neutralize it or destroy it
define antigen
antigens are anything that triggers a specific immune response
what happens in the third line of defence
immunity is the ability for the body to specifically counteract foreign substances or organisms called antigens. immune responses involve the production of proteins called antibodies and specialized lymphocytes
what are the two different lymphocytes involved in immunity and where do they mature
t cells- thymus
b cells- bone marrow
what is celll mediated immunity
cell mediated immunity is depends on t cells and does not involve antibody production. their primary response is to intracellular infections (virus)
what is humoral immunity
b cells produce antibodies to a specific antigen
describe natural active immunity
obtained when a person is exposed to an antigen naturally over exposure
describe natural passive immunity
transfer of antibodies from mother to infant via placenta or breastfeeding
describe artificial active immunity
the injection of a dead or dormant disease to help the body develop its own defence to
describe artificial passive immunity
antibodies that have been introduces into the body that have been extracted from an immune animal or person
what happens to our bodies following vaccinations which protect us from disease
vaccination deliberately exposes a person to a harmless version of a pathogen or toxin to stimulate their immune system to produce protective antibodies and memory cells but will not cause disease.
how does the immune system protect the body from disease
the immune system makes antibodies and uses them to specifically fight certain germs that the body has previously come into contact with
what methods do we use in hospitals to prevent transmission of diseases
antiseptic uses
frequent hand washing
active infection control programs
short hospital stays
define standard precautions
standard precautions are work practices required to achieve a basic level of infection control
give 4 examples of standard precautions
hand hygiene
PPE
safe use and disposal of sharps
routine environmental cleaning
how do additional precautions prevent the transmission of infectious diseases
additional precautions are takes while ensuring standard precautions are taking place. these are used when the standard precautions cant contain a disease alone.
state 3 examples of additional precautions
single rooms
negative pressure rooms
N95 masks
what are the 5 moments of hand hygiene
before touching a patient
before a procedure
after a procedure
after touching patient
after touching patient surroundings
when would we use disinfectant in healthcare
disinfectant elimanates many or all pathogenic microorganisms on inanimate objects with the exception of bacterial spores
when would we use anticeptic in healthcare
solutions used to disinfect skin and other living tissue.