lines of defence Flashcards

1
Q

what are the components of the first line of defence

A

skin
mucous membranes
normal flora

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2
Q

explain the role of the skin in immune defence

A

closely packed kerainised skin cells assist in resistance to entry of pathogens.

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3
Q

explain the role of mucous membranes in immune defence

A

the mucous layers inhibits the entrance of many microorganisms. the mucous traps pathogens before entering the body further.

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4
Q

explain the role of normal flora in immune defence

A

normal flora suppresses growth of pathogenic bacteria by competing for essential nutrients

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5
Q

state the components of the second line of defence

A

inflammation
fever
phagocytes and natural killer cutes
protective proteins

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6
Q

describe how inflammation defends us from infection

A

when cells or tissues are damaged, histamines are released and and triggers vasodilation which causes the heat, redness and swelling. the blood vessels are now more permeable. blood clots form around an abscess to prevent spreading of infection which destroys the agent.

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7
Q

describe how fever defends us from infection

A

bacterial endotoxins induce fever by stimulating the hypothalamus and release prostaglandins that reset the hypothalamic thermostat of the body.
increased temp=faster reactions.

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8
Q

describe how phagocytes and natural killer cells defends us from infection

A

phagocytes are a type of white blood cell that is responsible for engulfing and absorbing bacteria and other small cells and particles. natural killer cells are capable of destroying tumour cells.

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9
Q

describe how protective proteins defends us from infection

A

the complement system is the first part of the immune system that meets invaders like bacteria.
they react directly with antigens and trigger inflammation, attract phagocytes, coat intruder cells to make more appetizing and kill intruders.

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10
Q

what is inflammation and what are some advantages of having an inflammatory response

A

when cells or tissues are damaged, histamines are released and and triggers vasodilation which causes the heat, redness and swelling. the blood vessels are now more permeable. blood clots form around an abscess to prevent spreading of infection which destroys the agent.

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11
Q

define antibody

A

a specific protein produces in response to a substance foreign to the body that reacts with the antigen to neutralize it or destroy it

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12
Q

define antigen

A

antigens are anything that triggers a specific immune response

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13
Q

what happens in the third line of defence

A

immunity is the ability for the body to specifically counteract foreign substances or organisms called antigens. immune responses involve the production of proteins called antibodies and specialized lymphocytes

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14
Q

what are the two different lymphocytes involved in immunity and where do they mature

A

t cells- thymus
b cells- bone marrow

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15
Q

what is celll mediated immunity

A

cell mediated immunity is depends on t cells and does not involve antibody production. their primary response is to intracellular infections (virus)

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16
Q

what is humoral immunity

A

b cells produce antibodies to a specific antigen

17
Q

describe natural active immunity

A

obtained when a person is exposed to an antigen naturally over exposure

18
Q

describe natural passive immunity

A

transfer of antibodies from mother to infant via placenta or breastfeeding

19
Q

describe artificial active immunity

A

the injection of a dead or dormant disease to help the body develop its own defence to

20
Q

describe artificial passive immunity

A

antibodies that have been introduces into the body that have been extracted from an immune animal or person

21
Q

what happens to our bodies following vaccinations which protect us from disease

A

vaccination deliberately exposes a person to a harmless version of a pathogen or toxin to stimulate their immune system to produce protective antibodies and memory cells but will not cause disease.

22
Q

how does the immune system protect the body from disease

A

the immune system makes antibodies and uses them to specifically fight certain germs that the body has previously come into contact with

23
Q

what methods do we use in hospitals to prevent transmission of diseases

A

antiseptic uses
frequent hand washing
active infection control programs
short hospital stays

24
Q

define standard precautions

A

standard precautions are work practices required to achieve a basic level of infection control

25
Q

give 4 examples of standard precautions

A

hand hygiene
PPE
safe use and disposal of sharps
routine environmental cleaning

26
Q

how do additional precautions prevent the transmission of infectious diseases

A

additional precautions are takes while ensuring standard precautions are taking place. these are used when the standard precautions cant contain a disease alone.

27
Q

state 3 examples of additional precautions

A

single rooms
negative pressure rooms
N95 masks

28
Q

what are the 5 moments of hand hygiene

A

before touching a patient
before a procedure
after a procedure
after touching patient
after touching patient surroundings

29
Q

when would we use disinfectant in healthcare

A

disinfectant elimanates many or all pathogenic microorganisms on inanimate objects with the exception of bacterial spores

30
Q

when would we use anticeptic in healthcare

A

solutions used to disinfect skin and other living tissue.