Lifestyle factors and cardiovascular disease Flashcards

1
Q

What are the 3 leading causes of death in the UK and what percentage do they represent?

A

24% cardiovascular diseases

21% cancer (excluding lung cancer)

20% respiratory diseases

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2
Q

The onset and progression of cardiovascular diseases is strongly influenced by what?

A

Lifestyle (behaviour)

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3
Q

What percentage of cardiovascular disease would be prevented if there was elimination of modifiable risk factors - including unhealthy lifestyles?

A

80%

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4
Q

Via what 3 pathways does behaviour (including lifestyle) affect cardiovascular disease?

A

1] health-related behaviours such as diet, smoking, exercise

2] causing acute or chronic physiological changes that lead to CHD

3] access to, and use of medical care

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5
Q

Name 3 physical (immutable) risk factors for CVD

A

age

sex

family history other demographics

(genes)

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6
Q

Name 4 pyschosocial (modifiable) risk factors for CVD

A

health behaviours

stress

depression

social support

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7
Q

What are the clinical features of metabolic syndrome?

A

overweight and abdominal fat distribution, hypertension, insulin

resistance, hyperglycemia

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8
Q

EPIC-Norfolk study:

compared to those eating 5+ a day, other people were …

______ x more likely to die early from CVD

______ x more likely to have stroke

A
  1. 7
  2. 4
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9
Q

In the US Nurses Health Study:

compared to people in lowest 20% for total fat intake …

top 20% total fat = ______ x more likely to develop CVD

top 20% saturated fat = ______ x more likely to develop CVD

A
  1. 3
  2. 5
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10
Q

Can primary or secondary preventions -

improve diet

and = lower death rates (CVD and total)

= lower risk of further cardiac events

A

Secondary preventions

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11
Q

EPIC-Norfolk study:

compared to non-smokers, smokers were

_________ x more likely to die early from CVD

__________ x more likely to have stroke

A
  1. 9
  2. 7
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12
Q

Secondary prevention:

compared to CHD patients who keep smoking, quitters had

________ lower risk of premature death

__________ lower risk of another MI

A

36%

32%

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13
Q

EPIC-Norfolk study:

compared to active people, those below activity threshold were

_________ x more likely to die early from CVD

__________ x more likely to have stroke

A
  1. 3
  2. 3
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14
Q

Meta-anyalytic evidence shows that preventions can…

A

increase exercise

= reduce all-cause mortality

= reduce cardiovascular mortality

= reduce non-fatal cardiac events

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15
Q

lower social classes have greater CVD risk (Lynch et al., 1996)

compared with top 20% income, lowest 20% income have

________ x greater risk of CVD death

_________ x greater risk of acute MI

A
  1. 7
  2. 3
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16
Q

after adjustment for behavioural risk factors (smoking, diet, exercise) lowest 20% income have

no greater risk of CVD death

________ x greater risk of acute MI

A

2.8

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17
Q

Why do people risk their health?

A

biased risk perception
health optimism
general risk vs personal risk

18
Q

general public people acknowledge influence of various CVD risk factors
- but underestimate impact of what?

A

Diet and excersise

19
Q

“what do you think contributed to you having a heart attack?”

What are men more likely to cite?

A
  • poor diet
  • hard work
20
Q

“what do you think contributed to you having a heart attack?”

What are women more likely to cite?

A

chance or bad luck

21
Q

What are factors which decrease time to get to hospital with an MI?

A

= being male
= being married

= believing that MI has more serious consequences
= active coping style
= using problem-focused coping

= more non-pain symptoms (breathlessness, dizziness, etc.)

22
Q

What are the 4 types of response to stress and are they acute or chronic?

A

physical fight / flight response acute

behavioural poor diet, smoking, alcohol, drugs chronic

emotional anxiety, anger, depression chronic

cognitive poor concentration acute/chronic

23
Q

What are the 2 types of coping responses?

A

approach - problem-solving
avoidance - distraction - psychological or behavioural

24
Q

Name an epidemiological study that shows acute stress is associated with MI and cardiac death

A

MI and cardiac death after disasters
examples ? 9/11 terrorist attacks
football world cup

25
What have animal studies proven about chronic stress?
induces atherosclerosis lowers threshold for arrhythmia
26
What have experimental studies shown about acute stress?
triggers ischaemia in patients with CHD associated with cardiovascular changes (HR, BP)
27
Name 3 examples of how acute stress can trigger ischaemia in patients with CHD
intense physical activity stressful mental activity feeling tense, frustrated, angry, sad
28
What factors cause job stress to become chronic stress?
demands are high control is low support is low
29
What type of stress is associated with greater CVD risk?
Chronic stress
30
What is an individual vulnerability factor?
cardiac reactivity
31
Name examples of chronic risk Standard and pyschosocial
“standard” age sex family history smoking cholesterol hypertension “psychosocial” hostility depression low support chronic stress
32
Name examples of acute risk
33
Complete the diagram on accumulation of lifetime risk
34
What are the features of a type-A personalilty?
hard-driving competitive behaviour vigorous speech characteristics impatience potential for hostility
35
Is a type-A personality linked to cardiovascular disease?
may be a risk factor for CHD in healthy people not a risk for further problems in people with CHD hostility appears to be most important component
36
What is the emotional impact of a MI?
depression (up to 30%) anxiety symptoms (approx. 40%) PTSD (up to 15%)
37
depression is - ________ times more common after MI than at other times in life
2-3
38
Which mental illness is an independent predictor of premature death in CHD patients?
Depression
39
What is depression associated with a poorer adherence to post-MI?
associated with poorer adherence to medication or lifestyle modification post MI
40
How is depression treated?
via medication or psychotherapy can reduce depression and improve survival in MI patients with depression
41