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Pharmacology > Lidocaine, Amiodarone, Atropine, Adenosine > Flashcards

Lidocaine, Amiodarone, Atropine, Adenosine Flashcards

1
Q

Lidocaine classification

A

Ventricular antidisrhythmic

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2
Q

Lidocaine trade name

A

Xylocane

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3
Q

Lidocaine desired effect

A

Suppress ventricular ectopy,
raise v-fib threshold,
local anesthetic

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4
Q

Lidocaine mechanism of action

A

Decrease automaticity and refractory period in cardiac arrest

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5
Q

Lidocaine indications

A

Pulseless VT, stable VT, MI with ventricular ectopy, v-fib

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6
Q

Lidocaine contraindications

A

Allergic to amide anesthetic

Ventricular escape rhythm

2nd and 3nd AV blocks

Sinus arrest

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7
Q

Lidocaine adverse reactions

A

Seizure

Coma

Respiratory arrest

Hypotension

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8
Q

Lidocaine adult dosing
Cardiac arrest

A

1 - 1.5 mg/kg IV/IO
0.5-0.75 mg/kg IV/IO
Max 3 mg/kg

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9
Q

Lidocaine pediatric dosing
Cardiac arrest

A

1 mg/kg IV /IO

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10
Q

Amiodarone trade name

A

Cordarone

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11
Q

Amiodarone class

A

Antidisrhythmic

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12
Q

Amiodarone desired effects

A

Treat SVT and ventricular dysrhythmias

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13
Q

Amiodarone mechanism of action

A

Works on a myocardium to delay repolarization and depresses automaticity in the AV / SA node

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14
Q

Amiodarone indications

A

V-fib, pVT, wide complex tachycardia

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15
Q

Amiodarone contraindications

A

hypersensitivity,
2nd/3rd degree heart block,
Bradycardia
cardiogenic shock

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16
Q

Amiodarone adverse reactions

A

Hypotension, arrhythmia, heart block, sinus arrest

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17
Q

Amiodarone drug interactions

A

Increases digoxin levels and toxicity of lidocaine

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18
Q

Amiodarone dosing adult
V-fib/pVT

A

300 mg diluted in 20 to 30cc IVP
150 mg diluted in 20 to 30 cc IVP

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19
Q

Amiodarone dosing adult
Wide complex tachycardia

A

150 mg diluted in 20 to 30 cc

20
Q

Amiodarone pediatric dosing
V fib/ pVT

A

5 mg / kg diluted in 20 to 30 cc
Can repeat twice

21
Q

Amiodarone pediatric dosing
Wide complex

A

5 mg/kg diluted in 20 to 30 cc

22
Q

Atropine classification

A

Anticolinergic / parasympatholic

23
Q

Atropine trade name

A

Atropine

24
Q

Atropine desired effect

A

Accelerate heart rate in bradycardia
Dries mucus membranes in cholinergy poisoning

25
Q

Atropine mechanism of action
Effect 1:

A

Blocks Parasympathetic action (vagal)

26
Q

Atropine mechanism of action
Effect 2:

A

Increases SA node discharge

27
Q

Atropine mechanism of action
Effect 3:

A

Enhances conduction through AV junction

28
Q

Atropine indications

A

Symptomatic bradycardia,
2nd degree type 1 heart block,
cholinergic poisoning

29
Q

Atropine contraindications

A

AFib/aflutter with RVR
2ND degree type II AV block
3rd degree block
Myocardial ischemia

30
Q

Atropine adverse reactions

A

Tachycardia
delirium
headache

31
Q

Atropine drug interactions

A

Do not mix with sodium bicarbonate

32
Q

Atropine special considerations

A

Rapid IVP prevents reflex bradycardia

33
Q

Atropine adult dose
Bradycardia

A

1 mg rapid IVP every 3 to 5 minutes
Max 3 mg

34
Q

Atropine adult dosing
Cholinergic poisoning

A

2 mg rapid IVP/IM every 15 minutes

35
Q

Atropine pediatric dosing
Bradycardia

A

0.02 mg / kg rapid IVP every 5 minutes

Minimum 0.1 mg max 1 mg in children, Max 2 mg in adolescence

36
Q

Atropine pediatric dosing
Cholinergic poisoning

A

0.05 mg/kg IVP every 15 minutes
1 mg IM every 15 minutes

37
Q

Adenosine classification

A

Antidisrrhythmic

38
Q

Adenosine desired effect

A

Convert SVT and stable regular monomorphic wide complex tachycardia

39
Q

Adenosine mechanism of action

A

Slow AV conduction and interrupt reentry pathways through AV / SA node

40
Q

Adenosine Indications

A

Convert tache arrhythmias

41
Q

Adenosine contraindications

A

2ND / 3rd degree AV block
AFib/a flutter
Hypersensitivity

42
Q

Adenosine adverse reactions

A

Headache
Palpations
Chest pain
Shortness of breath
Nausea / vomiting
Hypotension

43
Q

Adenosine drug interactions

A

Caffeine/theophiline inhibits
Persantin prolongs

44
Q

Adenosine precautions

A

Caution in heart transplant patients

45
Q

Adenosine adult dosing

A

6 mg rapid IVP plus 20cc flush
12 mg rapid IVP plus 20 cc flush

46
Q

Adenosine pediatric dosing

A

0.1 mg/kg rapid IVP and 10cc flush (Max 6 mg)
0.2 mg/kg wrap it IVP and 10cc flush (Max 12 mg)

Pharmacology (4 decks)

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