Lid Disorders Flashcards
What is blepharospasm
Bilateral involuntary orbicularis oculi spasms
How to treat blepharospasm?
Botox every few weeks if debilitating
What is blepharoclonus?
Excessive blinking/spasming secondary to an ocular inflammation
What is myokymia?
Fasiculations of the orbiuclaris oculi (eye twitch) that is usually self limiting.
What can cause myokymia?
Stress, fatigue, medication or alcohol.
How to treat myokymia?
Coll compresses and topical antihistamines; want to increase refractory period of muscles so there is no quiver
What is pseudograefe?
Abnormaly regeneration of CNIII affecting the MR that attaches it to the levator palpebrae superioris; causes eye to elevate when abducting
What is angioedema with urticaria?
Allergies –> Swelling and hives. Caused by histamine release and causing severe swelling and red lesions.
How to treat angioedema with urticaria?
Antihistamines, cool compresses and possibly steroids
What are the three forms of Anthrax and which is ocular?
Cutaneous (ocular) , respiratory and intestional
Anthrax incidence is a large concern for which populations?
3rd world nations, people working with wool/cattle/farms
About how long does it take for symptoms to present in Anthrax?
Most often in about 2 weeks, but can be 1-2 days or up to 8 weeks.
When anthrax presents, it may look like what condition at first? (Signs and symptoms)
Preseptal cellulitis; no tenderness, no demarcation, no pain (usually), some itching, slight injection and redness
What is the disease process of anthrax?
Painless red rashes forming into papules becoming vesciular and maybe bullous. Eventually these ulcerate or hemorrhage, forming a black necrotic ulcer (eschar)
What’s the prognosis for anthrax? Treated and untreated?
80-90% spontaneously heal, remainder may have fatal results. Death is rare with proper systemic treatment
How to treat anthrax?
Vaccine; penicilin via IV, ciprofloxacin, maybe surgical repair if eschars severe
How does syphilis present?
Primary and secondary lid lesions with conjunctival involvement, madrosis, scleritis, interestitial keratitis
How to treat syphillis?
Penicilin
What’s elephantiasis?
Rarare parasitic infection causing lymphatic fluid to build up in subcutaneous tissue with severe allergic reaction and edema
What’s vaccinia (cow pox)?
Secondary to small pox vaccine, tends to self limit and leave a scar however. Caused by contamination from vaccination site
What’s madrosis?
Losing eyelashes
What’s poliosis?
White lashes
What’s xeroderma pigmentosum?
An autosomal recessive disorder where sunlight causes progressive pigmentation changes leading to scarring and possibly increased cancer rates (allergic to sun)
What’s erysipleas?
“Flesh eating disease” Strep. pyogenes secondary to a skin trauma.
How to treat erysipleas?
Oral antibiotics
What’s Erythema multiforme/Steven-Johnson syndrome?
Type IV hypersensitivity (DTH) usually to new medication. See a severe rash with perivascular inflammation (Bulls Eye Appearance)
What are the ocular signs to Steven Johnson syndrome?
Mucous discharge, pseudomembrane formation, papillary response, bullae formation, swollen crusty lids. Can even go into scarring, dry eye, iritis, corneal perforation, symblepharon, distchiasis, epiphoria, cictrical ectropion, and be FATAL
How to treat Steven Johnson Syndrome?
Electrolytes, systemic and topical steroids in high doses, may need a bandage CL
What’s cicatricial mean?
Scarring
How is Erythema multiforme similar to ocular cicatricial pemphigoid?
Both present with similar clinical appearances. Flu symptoms, severe rash with inflammation and a bulls eye appearance
How is Ocular Cicatricial pemphigoid different thant Erythema multiforme?
Age of onset is older in ocular cicatrical pemphigoid. Also in Steven Johnson syndrome more males are affected than females
What is Ocular Cicatricial Pemphigoid?
Late onset auto immune disorder affecting mucous membranes
How do you treat ocular cicatrical pemphigoid?
A supportive style, use AT, bandage lens, epilation, tarsorraphy, punctal plugs to best use whatever tears are left; use steroids and cyclophosphamide for immunosuppression
What’s impetigo?
A common staph infection seen in kids. A bug bite that you scratched causing a rash with crusted bullae
What’s Shingles?
Chicken pox virus, commonly affecting frontal nerve (upper lid and forehead and superior conj)
What’s Hutchinson Sign and what disorder is it associated with?
Tip of nose is red; associated with shingles and indicates nasociliary branch involvement (CNV)
Signs/Symptoms of Shingles?
Headache, fever, malaise, chills, PAIN, edema, scarring that can cause persistent pain, ptosis, ectropion, madrosis, entropion or lid retraction
How do you treat Shingles?
Usually self-limiting. But can give analgeics, prednisone, antidepressants for pain and oral antivirals (Acyclovir)
What’s Herpes Simplx?
A primary lesion acquired generally when an infected adults makes contact with a child. Leads to vesicles, that rupture, crust and heal.
How do you treat herpes simplex?
Preventative treatment to prevent corneal involvement, ACV cream, GCV gel, antibiotics to prevent secondary inflammations, drying agents to prevent oozing from ruptured crusts
What are the 5 kinds of blepharitis?
Staphylococcal Seborrheic Mixed Meibomiam gland dysfunction Meibomiam keratoconjunctivitis
What are the signs of all kinds of blepharitis?
Corneal/conjunctival staining, corneal lesions at 2, 4, 8 and 10 o clock, capped glands, reduced TBUT, greasy/crusty eyelashes, poliosis and madrosis and maybe pachyblepharon
What are the symptoms of all kinds of blepharitis?
Itching, burning (in mornings), dry eye (FBS), mattered lids, redness, puffiness, scratchiness, lash loss and maybe a hordeloum
How to assess blepharitis?
TBUT (reduced generally), bulbar conj staining (best seen with LIssamine green or maybe fluorscein), corneal stains (SPK), digital expression that may be turbid and associated with pus, palpebral conj is injected, has calcifued concretions, glands are yellow and plugged, some papillae, tortuous vessels (telangiectasia)
What’s Staph Blepharitis?
Caused by staph organism, see inflammation, collarettes, madrosis, seen in younger patients
What’s Seborrheic blepharitis?
95% associated with generalized seborrhea (excessive sebum being discharged); get chronic mild inflammation, greasy crusts, papillary response
What’s Meibomiam Gland Dysfunction?
Meibomiam glands overproduce sebaceous material and have a very rapid turnover of epithelial cells
What are some complications with MGD?
Causes a third of CL intolerance, associated with rosacea and generalized seborrhea, a precursor to MKC
What’s Meibomiam Keratoconjunctivitis?
Meibomiam gland dysnfunction that involves the cornea. A delayed type hypersensitivity and tend to also see scarring and vascularization. See thick discharge.
How is MKC different from MGD?
See keratitis, and corneal lesions in the 2, 4, 8 and 10 o clock positions where lid is closest to the eye.
How to treat MKC?
Variable, but tends to involve steroids due to the DTH reaction.
How are the grands of MGD classified? (0 to 4)
0 - All glands open
1 - 1-2 glands partially obstructed with clear fluid on expression
2 - 3+ partially obstructed with an obaque fluid on expression
3 - 1-2 BLOCKED glands with many partially blocked
4 - 3+ blocked glands with everything partially blocked
Blepharitis assocations: What’s demodex?
A mite that inhabits the lashes, believed through fecal matter is depositing staph aureus into the lashes
What’s the common name for keractoconjunctivitis sicca.
Dry eye