Lice (Treatments) Flashcards

1
Q

Permethrin
- MOA

A

Neurotoxic Insecticide
- Na+ Channel Disruptor
–> Delayed Repolarization of respiratory paralysis

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2
Q

Permethrin
- Direction

A
  1. Wash Hair (No Conditioner)
  2. Apply Permethrin 1% to wet hair
  3. Leave on for 10 mins then rinse
  4. Retreat in 7 days
  • Ensure to pull out lice and nits
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3
Q

Permethrin
- Side Effects

A

Transient Irritation (Redness + Swelling)

Ocular Toxicity

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4
Q

Permethrin
- Efficacy

A

96%-100%

Good Ovicidal Activity

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5
Q

Pyrethrin with Piperonyl Butoxide
- Mechanism

A

Neurotoxic Insecticide

Disrupts Na+ Channel
- Delays repolarization and prevents paralysis

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6
Q

Pyrethrin with Piperonyl Butoxide
- Directions

A
  1. Apply to Dry Hair
  2. Leave for 10 mins
  3. Lather and rinse with water
  4. Repeat in 7 days
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7
Q

Pyrethrin with Piperonyl Butoxide
- Side Effect

A

Mild Irritation
Contact Dermatitis
- (Petroleum in formulation)

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8
Q

Pyrethrin with Piperonyl Butoxide
- Efficacy

A

45% after 1st application
94% after 2nd application

Ovicidal Activity: 25-50%

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9
Q

Isopropyl Myristate / Cyclomethicone
- Mechanism

A

Dissolves Louse Exoskeleton
–> Dehydration –> Death

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10
Q

Isopropyl Myristate / Cyclomethicone
- Directions

A
  1. Apply to Dry Hair (Protect Eyes)
  2. Leave on for 10 mins
  3. Rinse
  4. Repeat in 7 days
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11
Q

Isopropyl Myristate / Cyclomethicone
- Side Effects

A

Local Irritation

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12
Q

Isopropyl Myristate / Cyclomethicone
- Efficacy

A

57-93%
No Ovicidal activity

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13
Q

Dimeticone
- Mechanism

A

Blocks Spiracle –> Suffocation

Inhibits Water Excretion –> Gut Rupture

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14
Q

Dimeticone
- Directions

A
  1. Spray on Dry Hair, massage until Hair is Wet
  2. Leave solution on hair for 30 min
  3. Comb hair
  4. Leave on for 8 hours
  5. Wash
  6. Repeat in 8-10 Days
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15
Q

Dimeticone
- Side Effect

A

Mild Skin Irritation
Irritation if contacts with eyes

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16
Q

Dimeticone
- Efficacy

A

97% Cure rate
100% Ovicidal Activity
- Still do a 2nd application due to imperfect application
(Lots of work but very effective)

17
Q
A