Lice (Treatments) Flashcards
Permethrin
- MOA
Neurotoxic Insecticide
- Na+ Channel Disruptor
–> Delayed Repolarization of respiratory paralysis
Permethrin
- Direction
- Wash Hair (No Conditioner)
- Apply Permethrin 1% to wet hair
- Leave on for 10 mins then rinse
- Retreat in 7 days
- Ensure to pull out lice and nits
Permethrin
- Side Effects
Transient Irritation (Redness + Swelling)
Ocular Toxicity
Permethrin
- Efficacy
96%-100%
Good Ovicidal Activity
Pyrethrin with Piperonyl Butoxide
- Mechanism
Neurotoxic Insecticide
Disrupts Na+ Channel
- Delays repolarization and prevents paralysis
Pyrethrin with Piperonyl Butoxide
- Directions
- Apply to Dry Hair
- Leave for 10 mins
- Lather and rinse with water
- Repeat in 7 days
Pyrethrin with Piperonyl Butoxide
- Side Effect
Mild Irritation
Contact Dermatitis
- (Petroleum in formulation)
Pyrethrin with Piperonyl Butoxide
- Efficacy
45% after 1st application
94% after 2nd application
Ovicidal Activity: 25-50%
Isopropyl Myristate / Cyclomethicone
- Mechanism
Dissolves Louse Exoskeleton
–> Dehydration –> Death
Isopropyl Myristate / Cyclomethicone
- Directions
- Apply to Dry Hair (Protect Eyes)
- Leave on for 10 mins
- Rinse
- Repeat in 7 days
Isopropyl Myristate / Cyclomethicone
- Side Effects
Local Irritation
Isopropyl Myristate / Cyclomethicone
- Efficacy
57-93%
No Ovicidal activity
Dimeticone
- Mechanism
Blocks Spiracle –> Suffocation
Inhibits Water Excretion –> Gut Rupture
Dimeticone
- Directions
- Spray on Dry Hair, massage until Hair is Wet
- Leave solution on hair for 30 min
- Comb hair
- Leave on for 8 hours
- Wash
- Repeat in 8-10 Days
Dimeticone
- Side Effect
Mild Skin Irritation
Irritation if contacts with eyes