LFTs Flashcards
(18 cards)
Where in the cell and in what cell types is Apartate Aminotransferase (AST) found
RBC’s, pancreas, kidney, liver, sk mus, cardiac mus
Normal Alanine Aminotransferase (ALT) level
4-40 IU/L
Where in the cell and in what cell type is ALT enzyme found
cytosol of liver; skeletal muscle, cardiac muscle, liver tissue
Normal AST values
0-35 IU/L
Which cell types contain Alkaline Phosphatase (ALP)
Many. But think liver, bone and biliary tract epithelium
What is the normal ALP value
30-120 IU/L
How would you follow up elevated ALP level (3)
Fractionated ALP: ALP1 isoenzyme (liver), ALP2 isoenzyme (bone); GGT (if normal, then bone); 5’NT
What cell types contain GGT (Gamma-Glutamyl Transpeptidase)
many, but think hepatic and especially BILE TRACT
Normal value for GGT
8-38 IU/L lower for females less than 45 yrs
Normal Albumin level
3-6g/dL
Normal 5’NT level
0-1.6 IU/L
What cell types contain 5’NT
only liver cells
Normal Prothrombin Time
11-13 seconds
Normal Serum ammonia level
10-80 mcg/L
What is the normal total bilirubin value
0.3-1.0 mg/dL (with indirect measurement contributing the most to this value)
higher AST/ALT ratio indicates this state
alcohol related liver disease
ALT/AST ratio is higher means this state
fatty liver disease
In what condition will both unconjugated and conjugated serum bilirubin be increased
hepatic jaundice
