LFTs

Question 0

Where in the cell and in what cell types is Apartate Aminotransferase (AST) found

Answer 0

RBC’s, pancreas, kidney, liver, sk mus, cardiac mus

Question 1

Normal Alanine Aminotransferase (ALT) level

Answer 1

4-40 IU/L

Question 2

Where in the cell and in what cell type is ALT enzyme found

Answer 2

cytosol of liver; skeletal muscle, cardiac muscle, liver tissue

Question 3

Normal AST values

Answer 3

0-35 IU/L

Question 4

Which cell types contain Alkaline Phosphatase (ALP)

Answer 4

Many. But think liver, bone and biliary tract epithelium

Question 5

What is the normal ALP value

Answer 5

30-120 IU/L

Question 6

How would you follow up elevated ALP level (3)

Answer 6

Fractionated ALP: ALP1 isoenzyme (liver), ALP2 isoenzyme (bone); GGT (if normal, then bone); 5’NT

Question 7

What cell types contain GGT (Gamma-Glutamyl Transpeptidase)

Answer 7

many, but think hepatic and especially BILE TRACT

Question 8

Normal value for GGT

Answer 8

8-38 IU/L lower for females less than 45 yrs

Question 9

Normal Albumin level

Answer 9

3-6g/dL

Question 10

Normal 5’NT level

Answer 10

0-1.6 IU/L

Question 11

What cell types contain 5’NT

Answer 11

only liver cells

Question 12

Normal Prothrombin Time

Answer 12

11-13 seconds

Question 13

Normal Serum ammonia level

Answer 13

10-80 mcg/L

Question 14

What is the normal total bilirubin value

Answer 14

0.3-1.0 mg/dL (with indirect measurement contributing the most to this value)

Question 15

higher AST/ALT ratio indicates this state

Answer 15

alcohol related liver disease

Question 16

ALT/AST ratio is higher means this state

Answer 16

fatty liver disease

Question 17

In what condition will both unconjugated and conjugated serum bilirubin be increased

Answer 17

hepatic jaundice