LFTs Flashcards

1
Q

↑ ALT (3)

A

Primary liver disease
Biliary obstruction
Pancreatitis

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2
Q

ALT>AST

A

Viral hepatitis

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3
Q

AST>ALT

A

Alcoholic liver disease

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4
Q

↑ ALP (6)

A
Biliary obstruction
Primary liver disease
Infiltrative liver disease
Bone diseases
Hyperparathyroidism
Hyperthyroidism
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5
Q

Hepatocellular injury

A

> 10x increase in ALT + <3x increase in ALP

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6
Q

> 10x increase in ALT + <3x increase in ALP

A

Hepatocellular injury

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7
Q

Cholestasis

A

<10x increase in ALT + >3x increase in ALP

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8
Q

<10x increase in ALT + >3x increase in ALP

A

Cholestasis

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9
Q

What does ALT generally indicate

A

Hepatocellular injury

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10
Q

What does ALP + GGT generally indicate

A

Cholestasis

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11
Q

What increases GGT (4)

A

Biliary epithelial damage
Bile flow obstruction
Alcohol
Phenytoin

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12
Q

Normal urine + normal stools

A

Pre hepatic cause

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13
Q

Pre hepatic cause

A

Normal urine + normal stools

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14
Q

Dark urine + normal stools

A

Hepatic cause

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15
Q

Hepatic cause

A

Dark urine + normal stools

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16
Q

Dark urine + pale stools

A

Post hepatic cause (obstructive)

17
Q

Post hepatic cause (obstructive)

A

Dark urine + pale stools

18
Q

ALT>AST

A

Chronic liver disease

19
Q

AST>ALT

A

Cirrhosis + acute alcoholic hepatitis