Lexture 4 (Exam 2) Flashcards
What are the 2 essential fatty acids?
- Linoleic acid
- Alpha-linolenic acid
Why are the 2 essential fatty acids conditional?
Because they serve as precursor molecules
Linoleic acid is a precursor for what?
Arachidonic acid (AA) (which is pro-inflammatory)
ALA is a precursor for what?
EPA and DHA (which are anti-inflammatory)
Which are the omega-6 FAs?
- Linoleic acid (LA)
- Arachidonic Acid (AA)
Which are the omega-3 FAs?
- ALA (alpha linolenic acid)
- EPA (Eicosapentaenoic acid)
- DHA (Docosahexaeonic acid)
What foods contain linoleic acid?
Vegetable oils
Safflower oils
What foods contain arachidonic acid?
Meat
Poultry
Eggs
What foods contain ALA?
Green leafy vegetables
Flax and chia seeds
Canola, walnut, soybean oils
What foods contain EPA?
Oily fish
Krill oil
Algae oil
What foods contain DHA?
Oily fish
Krill oil
Algae oil
What are the functions of PUFAs?
Whether they are biosynthesized from the body or taken in through the diet:
1) Serve as an energy source through oxidation
2) CM fluidity
When released from CM via PHOSPHOLIPASE:
3) Effect gene expression
4) Be converted to eicosanoids
Saturated fats do what to the cell membrane?
Provide stiffness and structure
What are the 4 types of eicosanoids?
1) Prostaglandins
2) Thromboxanes
3) Leukotrienes
4) Resolvins
What are eicosanoids generally?
They serve as potent compounds; acting as ‘second messengers,’ which can elicit a wide range of responses (inflamm, anti-inflamm, pathologic/hypersensitivit)
