Lewy-Body Dementia

Question 1

Lewy-Body Dementia Pathogenesis

Answer 1

• Lewy bodies

- Spectrum of Lewy body disorders that may overlap, include DLB, Parkinson’s (depends where Lewy bodies deposit)

Question 2

Lewy-Body Dementia Epidemiology

Answer 2

-Third most common

Question 3

Lewy-Body Dementia Presentation

Answer 3

• Three core features
• Fluctuating awareness and attention
• Mild Parkinsonism
• Visual hallucinations
• Sleep disorders
• Fainting

Question 4

Lewy-Body Dementia Differentials

Answer 4

• Other forms of dementia
• Parkinson’s
• Intracranial tumours

Question 5

Lewy-Body Dementia Ix

Answer 5

• Usually clinical diagnosis
• Dementia screen
• SPECT

Question 6

Lewy-Body Dementia Management

Answer 6

• Antipsychotics may worsen neurological symptoms and vice versa
• Can use AChEi