Leukotriene Receptor Antagonists Flashcards

1
Q

Give examples of leukotriene receptor antagonists (LTRAs).

A

Montelukast, zafirlukast.

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2
Q

How do leukotriene receptor antagonists work?

A

Block the effects of inflammatory mediators called leukotrienes, in the airways.

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3
Q

There is a risk of hepatic disorders with the use of leukotriene receptor antagonists (LTRAs), especially with zafirlukast. What signs and symptoms may indicate this?

A

Persistent nausea, vomiting, malaise, jaundice, dark urine.

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4
Q

Churg-Strauss syndrome is a rare complication seen with leukotriene receptor antagonist. What are the signs and symptoms of this?

A

Eosinophilia, vasculitic rash, worsening pulmonary symptoms, cardiac complications, peripheral neuropathy.

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