Leukotriene Modulators Flashcards

1
Q

Montelukast (Singulair)

A

Tablets or granule packets

1-Adults

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2
Q

Zafirlukast (Accolate)

A

Tablets

5-Adults

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3
Q

Zileuton (Zyflo)

A

ER and IR tablets

Adults

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4
Q

Adverse effects

A

Neuropsychiatric events (agitation, anxiety, dreams, hallucinations, depression)

Churg Syndrome

Increased hepatic transaminases (Zafirlukast & Zileuton)

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5
Q

Counseling tips

A

Not used with COPD

Zafirlukast: at least 1-2 hr before meals, can increase INR

Zileuton: take with food

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