Leukocytes | White Blood Cells Flashcards by Taylor Davison

Neutrophils (Segs) are visually distinct during a differential by their?

Dark, dense nucleus that can be any shape
with a Clear cytoplasm.
May have light pink dust like granuals

How well did you know this?

Not at all

Perfectly

are visually distinct during a differential by their?

Neutrophils (Segs)

How well did you know this?

Not at all

Perfectly

Band Neutrophils are visually distinct during a differential by their?

Horseshoe shaped nucleus
Smooth margins to nucleus, any indentation must be less than 1/3 the width of nucleus

How well did you know this?

Not at all

Perfectly

Lymphocytes are visually distinct during a differential by their?

Large, round, dense nucleus
Round cell
Little cytoplasm, blue cytoplasm

How well did you know this?

Not at all

Perfectly

Immunocytes are visually distinct during a differential by their?

Larger cell, more cytoplasm
Dark blue edge to membrane

How well did you know this?

Not at all

Perfectly

Monocytes are visually distinct during a differential by their?

Large cell
Lacy nucleus (can be any shape)
Blue gray cytoplasm
Can have vacuoles

How well did you know this?

Not at all

Perfectly

Band Neutrophils are?

Immature Neutrophils pushed into circulation prematurely

How well did you know this?

Not at all

Perfectly

Name the White Blood Cell:

Lymphocyte

How well did you know this?

Not at all

Perfectly

Name the White Blood Cell:

Lymphocyte

How well did you know this?

Not at all

Perfectly

Immunocytes are?

Antigenically stimulated lymphocyte

How well did you know this?

Not at all

Perfectly

Name the White Blood Cell:

Immunocytes

How well did you know this?

Not at all

Perfectly

Name the White Blood Cell:

Immunocyte

How well did you know this?

Not at all

Perfectly

Name the White Blood Cell:

Monocyte

How well did you know this?

Not at all

Perfectly

Name the White Blood Cell:

Monocyte

How well did you know this?

Not at all

Perfectly

Eosinophils are visually distinct during a differential by their?

Granules some shade of red
Can see light through granules

How well did you know this?

Not at all

Perfectly

Name the White Blood Cell:

Eosinophil

How well did you know this?

Not at all

Perfectly

Name the White Blood Cell:

Eosinophil

How well did you know this?

Not at all

Perfectly

Define: Antigen (Ag)

substance that elicits (triggers) specific immune response when present in the body

How well did you know this?

Not at all

Perfectly

Define: Antibody (Ab)

– specialized protein produced in response to an Antigen (Ag) - gamma globulins (immunoglobulins )

How well did you know this?

Not at all

Perfectly

Antibody IgG, IgM protect against?

bacteria, viruses

How well did you know this?

Not at all

Perfectly

Antibody IgE protect against?

– allergic responses

How well did you know this?

Not at all

Perfectly

Antibody IgA protect against?

protect GI, urogenital, & respiratory tracts

How well did you know this?

Not at all

Perfectly

Antibody IgD protect against?

present on the surface of some lymphocytes (B-lymphs) which initiate a humoral immune response

How well did you know this?

Not at all

Perfectly

lymphocytes (B- lymphs) role in immunity is?

initiate humoral immune response

How well did you know this?

Not at all

Perfectly

Neutrophils function are?

- First line of defense against infection by migrating to any area invaded by bacteria - Can also break down necrotic tissue - Highly phagocytic and motile

Average transit time for neutrophils in blood is?

10 hours

All neutrophils are replaced every?

about 2.5/day

Neutrophils move from ______ into _____ Once in tissues, cannot come back into _____ . & are lost where?

Neutrophils move from the bloodstream into the tissues & Once in the tissues they cannot come back into the blood stream. Lost in secretions, excretions through mucous membranes

Eosinophils function are?

- Ingest products of Ab/Ag reactions - Attracted by & inhibit allergic/anaphylactic reactions - Anti-parasitic - Phagocytic - Bactericidal - Normally scarce in blood stream but will see an Increase during parasitic infections & hypersensitivity (allergic reactions)

Basophils function are?

Role in immunity unclear Release Histamine & Heparin

Lymphocytes function are?

- Main function is immunity - Lymphocytes can form hundreds of different types of sensitized lymphocytes and antibodies. Each type is specific for a particular antigen and is capable of multiplying into large numbers of clones when excited by that antigen. - Antigens stimulate B-lymphocytes to divide and/or transform into cells that produce immunoglobulins (Ab)

What are the two type of Lymphocytes?

1. T-Lymph Cells 2. B-Lymph Cells

What are T Lymphocytes (T Cells)?

Cell Mediated Immunity. “Free Floating” - Has antigens receptors on surface of their body cells that allow them to give specific immune response to INTRACELLULAR phase of viral infection,fungi, parasites, bacteria. - Does NOT secrete antibodies. - Will lyse or kill body cells to get to the infection. - They attract neutrophils to phagocyte the dead cells.

What are B Lymphocytes (B Cells)?

Humoral immunity - Deal with antibodies that are free floating in the EXTRACELLULAR fluid blood, plasma, and lymph - Produces antibodies & release them into blood and lymph against various of antigens - Specific immune resistance to most bacteria, extracellular phase of viral infections - Antibodies produced by plasma cells circulate as what are now called free gamma globulin that are essentially plasma proteins - Some B cells divide into memory cells

About what percent of lymphocytes are seen in the blood stream?

10%

The majority of Lymphocytes seen on a blood smear are?

T cells since they are free floating

T Cells travel via the?

Bloodstream to the thymus gland where they mature & are introduced to “self” & sent back into the bloodstream to hangout & wait for antigens

B cells travel via?

The bloodstream to the liver, spleen & lymph nodes where they mature & stay.

The average transient time for Lymphocytes in the blood?

30 mins.

Where are Increased numbers of lymphocytes seen?

in the lymph nodes & spleen

What are Monocytes function?

Eat all the big chunky stuff - Phagocytosis and digestion of particulate and cellular debris.

What are produced by Monocytes?

1. Interferon Proteins 2. Transferrin Proteins

What is Interferon?

A protein produced by Monocytes when the body is exposed to viral antigens & has Ant-Tumor qualities.

What is Transferrin?

∆ A protein produced by monocytes that transport Iron

monocyte blood transit time is?

24-36 hours

What are Macrophages? & there function?

∆ Large phagocytic cells. ∆ Monocytes that have left the blood vessels and entered the tissues where they grew very large in size. Function: ∆ Ingest bacteria and other foreign substances

What percentage of Neutrophils are seen in Dogs?

60-70%

What percentage of Lymphocytes are seen in Dogs?

10-40%

What percentage of Eosinophils are seen in Dogs?

0-10%

What percentage of Monocytes are seen in Dogs?

0-10%

What percentage of Basophils are seen in Dogs?

Rare

What percentage of Neutrophils are seen in Feline?

60-70%

What percentage of Lymphocytes are seen in Feline?

10-40%

What percentage of Eosinophils are seen in Feline?

0-10%

What percentage of Monocytes are seen in Feline?

0-10%

What percentage of Basophils are seen in Feline?

Rare

What percentage of Neutrophils are seen in Equine?

60-70%

What percentage of Lymphocytes are seen in Equine?

10-40%

What percentage of Eosinophils are seen in Equine?

0-10%

What percentage of Monocytes are seen in Equine?

0-10%

What percentage of Basophils are seen in Equine?

Rare. Besides in old horses

What percentage of Neutrophils are seen in Bovine?

10-40%

What percentage of Lymphocytes are seen in Bovine?

60-70%

What percentage of Eosinophils are seen in Bovine?

0-10%

What percentage of Monocytes are seen in Bovine?

0-10%

What percentage of Basophils are seen in Bovine?

Rare